(Q34221944)

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Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition

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scholarly article

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Europe PubMed Central

31 July 2017

Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition (English)

1 reference

Europe PubMed Central

31 July 2017

Shih-Chung Chang

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Shih-Chung Chang

2

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Chiao-Yin Sun

1

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Europe PubMed Central

31 July 2017

Mai-Szu Wu

3

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Europe PubMed Central

31 July 2017

language of work or name

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30 March 2012

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

7

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Europe PubMed Central

31 July 2017

3

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Europe PubMed Central

31 July 2017

e34026

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Europe PubMed Central

31 July 2017

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Creative Commons Attribution 4.0 International

30 March 2012

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April 2022 Public Data File from Crossref

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0 references

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer

1 reference

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5 July 2018

Snail involves in the transforming growth factor β1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells

1 reference

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5 July 2018

Blocking core fucosylation of TGF-β1 receptors downregulates their functions and attenuates the epithelial-mesenchymal transition of renal tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Epithelial and mesenchymal phenotypic switchings modulate cell motility in metastasis

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5 July 2018

Human cytomegalovirus induces TGF-β1 activation in renal tubular epithelial cells after epithelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Angiotensin II and its role in tubular epithelial to mesenchymal transition associated with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress

1 reference

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5 July 2018

TGFβ and EGF synergistically induce a more invasive phenotype of epithelial ovarian cancer cells

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5 July 2018

Transforming growth factor-{beta}1 induces Smad3-dependent {beta}1 integrin gene expression in epithelial-to-mesenchymal transition during chronic tubulointerstitial fibrosis

1 reference

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5 July 2018

Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.

1 reference

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5 July 2018

Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

An integrative view on the role of TGF-beta in the progressive tubular deletion associated with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

New insights into epithelial-mesenchymal transition in kidney fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

p-Cresyl sulfate and indoxyl sulfate in hemodialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

New insights into uremic toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Pharmacological modulation of epithelial mesenchymal transition caused by angiotensin II. Role of ROCK and MAPK pathways.

1 reference

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5 July 2018

Novel aspects of the renin-angiotensin-aldosterone-system

1 reference

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5 July 2018

Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro

1 reference

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5 July 2018

Renin-angiotensin-aldosterone system and progression of renal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Transforming growth factor-beta and Smad signalling in kidney diseases.

1 reference

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5 July 2018

Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Halting the progression of chronic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

Protein-bound uremic solutes: the forgotten toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316590

5 July 2018

P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034026

21 January 2018

[Epithelial mesenchymal transition during development in fibrosis and in the progression of carcinoma]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoxyl sulfate increases the gene expressions of TGF-beta 1, TIMP-1 and pro-alpha 1(I) collagen in uremic rat kidneys

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoxyl sulfate stimulates renal synthesis of transforming growth factor-beta 1 and progression of renal failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of dihydrotestosterone in immortalized mouse proximal tubule cells. Technical note

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0034026

1 reference

Europe PubMed Central

31 July 2017

2012PLoSO...734026S

0 references

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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