(Q34222291)

English

Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

portal hypertension

1 reference

based on heuristic

inferred from title

author name string

Wei Luo

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Ying Meng

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Hong-Li Ji

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Chun-Qiu Pan

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Shan Huang

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Chang-Hui Yu

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Li-Ming Xiao

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Kai Cui

8

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Shu-Yuan Ni

9

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Zhen-Shu Zhang

10

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Xu Li

11

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Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

30 March 2012

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

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Europe PubMed Central

PubMed publication ID

31 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e34230

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

30 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Renin-angiotensin-aldosterone inhibitors in the reduction of portal pressure: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension

1 reference

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5 July 2018

Mechanisms of hepatic fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Current concepts on the pathophysiology of portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Dynamic expression of extracellular signal-regulated kinase in rat liver tissue during hepatic fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Rho GTPases, statins, and nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Portal hypertension: from bedside to bench.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Aldosterone-induced inflammation in the rat heart : role of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Effect of aldosterone on collagen steady state levels in primary and subcultured rat hepatic stellate cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Complications of cirrhosis. I. Portal hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Reduction in hepatic venous pressure gradient as a consequence of volume contraction due to chronic administration of spironolactone in patients with cirrhosis and no ascites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

5 July 2018

Angiotensin II and Aldosterone stimulating NF-kappaB and AP-1 activation in hepatic fibrosis of rat.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Mineralocorticoid receptor antagonist spironolactone prevents pig serum-induced hepatic fibrosis in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Roles of anandamide in the hepatic microcirculation in cirrhotic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Elucidation of the role of COX-2 in liver fibrogenesis using transgenic mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Mineralocorticoid receptor antagonism in experimental atherosclerosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Three-day tetrahydrobiopterin therapy increases in vivo hepatic NOS activity and reduces portal pressure in CCl4 cirrhotic rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal hypertension.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034230

21 January 2018

Gene-CYP11B2 expression in rat liver in hepatic fibrogenesis induced by CCl4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316615

28 October 2018

Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP11B2 expression in rat liver and the effect of spironolactone on hepatic fibrogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0034230

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...734230L

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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