(Q34229596)

31 July 2017

title

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress (English)

1 reference

31 July 2017

Laura Leung

1

1 reference

31 July 2017

Mandy Kwong

2

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31 July 2017

Stephen Hou

3

1 reference

31 July 2017

Candy Lee

4

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31 July 2017

Jefferson Y Chan

5

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31 July 2017

language of work or name

English

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publication date

10 September 2003

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Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

278

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31 July 2017

issue

48

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31 July 2017

page(s)

48021-48029

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Antioxidant response element

31 July 2017

cites work

1 reference

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The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines

21 January 2018

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Regulation of gene expression by reactive oxygen

21 January 2018

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

21 January 2018

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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

21 January 2018

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Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast

21 January 2018

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Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

21 January 2018

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Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

21 January 2018

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Isolation of cDNA encoding the human NF-E2 protein

21 January 2018

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Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

21 January 2018

1 reference

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Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site

21 January 2018

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Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

21 January 2018

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Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice

21 January 2018

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The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development

21 January 2018

1 reference

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NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

21 January 2018

1 reference

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

1 reference

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Nrf2 is essential for protection against acute pulmonary injury in mice

21 January 2018

1 reference

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Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

21 January 2018

1 reference

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

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Role of NRF2 in protection against hyperoxic lung injury in mice

21 January 2018

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

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Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

21 January 2018

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

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The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts

21 January 2018

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21 January 2018

p53: good cop/bad cop.

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Live or let die: the cell's response to p53

21 January 2018

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Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

21 January 2018

1 reference

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

1 reference

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Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

21 January 2018

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Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).

21 January 2018

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Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene.

21 January 2018

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The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

21 January 2018

1 reference

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Glutathione synthesis is essential for mouse development but not for cell growth in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

21 January 2018

1 reference

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Biogenesis of mitochondria during Xenopus laevis development.

21 January 2018

1 reference

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

1 reference

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Regulatory mechanisms of cellular response to oxidative stress

21 January 2018

1 reference

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Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

21 January 2018

1 reference

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Comprehensive Analysis of Proteins Which Interact with the Antioxidant Responsive Element: Correlation of ARE-BP-1 with the Chemoprotective Induction Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

Glucose metabolism in separated embryos and investing membranes during organogenesis in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

Energy metabolism during mammalian embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

Mechanisms of p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308439200

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M308439200

1 reference

31 July 2017

1 reference