(Q63408383)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719722%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation (English)

1 reference

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3 November 2019

1 reference

1 reference

7

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3 November 2019

author name string

Schuler M

1

1 reference

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3 November 2019

Maurer U

2

1 reference

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3 November 2019

Goldstein JC

3

1 reference

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3 November 2019

Breitenbücher F

4

1 reference

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3 November 2019

Hoffarth S

5

1 reference

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3 November 2019

Waterhouse NJ

6

1 reference

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3 November 2019

publication date

1 April 2003

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Cell Death & Differentiation

3 November 2019

published in

1 reference

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3 November 2019

volume

10

1 reference

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3 November 2019

page(s)

451-460

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3 November 2019

issue

4

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401180

3 November 2019

exact match

0 references

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Role of the INK4a locus in tumor suppression and cell mortality.

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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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7 January 2021

Essential role for oncogenic Ras in tumour maintenance

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7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

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7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

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7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

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7 January 2021

A model for p53-induced apoptosis

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7 January 2021

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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7 January 2021

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

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7 January 2021

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

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7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

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7 January 2021

Mitochondria and apoptosis

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7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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7 January 2021

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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7 January 2021

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

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7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

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7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

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7 January 2021

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

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7 January 2021

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

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7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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7 January 2021

Role of BAX in the apoptotic response to anticancer agents

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7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

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7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

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7 January 2021

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

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7 January 2021

Apoptotic pathways: the roads to ruin

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7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

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7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

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7 January 2021

Structure of Bax: coregulation of dimer formation and intracellular localization

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7 January 2021

Essential role for caspase-8 in transcription-independent apoptosis triggered by p53

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7 January 2021

Characterization of distinct consecutive phases in non-genotoxic p53-induced apoptosis of Ewing tumor cells and the rate-limiting role of caspase 8.

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7 January 2021

Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis

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7 January 2021

Regulation of the p53 tumor suppressor protein

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7 January 2021

Primary cells suppress oncogene-dependent apoptosis

1 reference

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7 January 2021

p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

1 reference

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7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

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7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

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7 January 2021

Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

RNA interference: the new somatic cell genetics?

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7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

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7 January 2021

Stable suppression of tumorigenicity by virus-mediated RNA interference

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7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

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7 January 2021

Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria

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7 January 2021

BH3-Only proteins-essential initiators of apoptotic cell death

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7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

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7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

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7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021