(Q34229644)

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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease (English)

1 reference

Europe PubMed Central

31 July 2017

Alzheimer's disease

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blood–brain barrier

1 reference

based on heuristic

inferred from title

William E. Sonntag

object named as

William E Sonntag

8

0 references

9

object named as

Zoltan Ungvari

1 reference

Europe PubMed Central

31 July 2017

Zsuzsanna Tucsek

1

object named as

Zsuzsanna Tucsek

1 reference

Europe PubMed Central

31 July 2017

2

object named as

Peter Toth

1 reference

Europe PubMed Central

31 July 2017

author name string

Danuta Sosnowska

3

1 reference

Europe PubMed Central

31 July 2017

Tripti Gautam

4

1 reference

Europe PubMed Central

31 July 2017

Matthew Mitschelen

5

1 reference

Europe PubMed Central

31 July 2017

Akos Koller

6

1 reference

Europe PubMed Central

31 July 2017

Gabor Szalai

7

1 reference

Europe PubMed Central

31 July 2017

Anna Csiszar

10

1 reference

Europe PubMed Central

31 July 2017

language of work or name

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publication date

22 November 2013

1 reference

Europe PubMed Central

31 July 2017

The Journals of Gerontology

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Europe PubMed Central

31 July 2017

69

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Europe PubMed Central

31 July 2017

10

1 reference

Europe PubMed Central

31 July 2017

1212-1226

1 reference

Europe PubMed Central

31 July 2017

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

1 reference

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Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats

1 reference

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Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

1 reference

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Associations between arterial elasticity and markers of inflammation in healthy older women.

1 reference

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Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.

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Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

1 reference

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6 July 2018

Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice

1 reference

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Total and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach

1 reference

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The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

1 reference

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Long-term assessment of inflammation and healthy aging in late life: the Cardiovascular Health Study All Stars

1 reference

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6 July 2018

Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet

1 reference

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Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?

1 reference

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Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

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6 July 2018

Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Adiponectin-deficiency exaggerates sepsis-induced microvascular dysfunction in the mouse brain

1 reference

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6 July 2018

The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Longitudinal changes in adiponectin and inflammatory markers and relation to survival in the oldest old: the Cardiovascular Health Study All Stars study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Endogenous secretory receptor for advanced glycation end products is associated with low serum interleukin-1 receptor antagonist and elevated IL-6 in older community-dwelling adults

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Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.

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Intrinsic depot-specific differences in the secretome of adipose tissue, preadipocytes, and adipose tissue-derived microvascular endothelial cells

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6 July 2018

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

NOX activity in brain aging: exacerbation by high fat diet.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Cognitive impairment following high fat diet consumption is associated with brain inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet

1 reference

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Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice.

1 reference

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Macrophage infiltration into adipose tissue: initiation, propagation and remodeling.

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Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus.

1 reference

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Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat

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Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: an epidemiological perspective

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Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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The blood-brain barrier in health and chronic neurodegenerative disorders

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue

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Fcgamma receptors as regulators of immune responses

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Aging up-regulates expression of inflammatory mediators in mouse adipose tissue

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

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Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study

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Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.

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Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells

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Microglia in the aging brain

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Regulation of large cerebral arteries and cerebral microvascular pressure

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172034

6 July 2018

Surrogate measures of insulin resistance: of rats, mice, and men.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice.

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https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Age-related differences in inflammatory markers in men: contribution of visceral adiposity.

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https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

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21 January 2018

Microglial activation in neuroinflammation: implications for the etiology of neurodegeneration.

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https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

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https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice.

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https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2FGLT177

21 January 2018

Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24269929

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mid-life adiposity factors relate to blood-brain barrier integrity in late life

1 reference

https://pubmed.ncbi.nlm.nih.gov/24269929

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/GERONA/GLT177

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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