(Q34229760)

English

Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints

scientific article published on 4 April 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Mycobacterium tuberculosis

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Nicolaas C Gey van Pittius

object named as

Nicolaas C Gey van Pittius

8

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Robin M. Warren

object named as

Robin M Warren

7

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object named as

Ruben Cloete

2

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Anita C. Schürch

object named as

Anita C Schürch

4

0 references

3

object named as

Borna Müller

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Sébastien Gagneux

6

object named as

Sebastien Gagneux

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Paul van Helden

5

object named as

Paul D van Helden

1 reference

Europe PubMed Central

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31 July 2017

author name string

Christopher R E McEvoy

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

4 April 2012

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e30593

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

4 April 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

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Strong antibody responses to Mycobacterium tuberculosis PE-PGRS62 protein are associated with latent and active tuberculosis.

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Frequent homologous recombination events in Mycobacterium tuberculosis PE/PPE multigene families: potential role in antigenic variability

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Characterization of T-cell immunogenicity of two PE/PPE proteins of Mycobacterium tuberculosis

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Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

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Mycobacterium tuberculosis PE_PGRS16 and PE_PGRS26 genetic polymorphism among clinical isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Mycobacterial PE_PGRS proteins contain calcium-binding motifs with parallel beta-roll folds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Selection of genes of Mycobacterium tuberculosis upregulated during residence in lungs of infected mice

1 reference

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PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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DNA polymorphisms in the pepA and PPE18 genes among clinical strains of Mycobacterium tuberculosis: implications for vaccine efficacy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Differential B-cell responses are induced by Mycobacterium tuberculosis PE antigens Rv1169c, Rv0978c, and Rv1818c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Association of Mycobacterium tuberculosis PE PGRS33 polymorphism with clinical and epidemiological characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair

1 reference

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Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

1 reference

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Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha

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Spoligotype signatures in the Mycobacterium tuberculosis complex.

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Evidence for recombination in Mycobacterium tuberculosis

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Identification of a repetitive sequence belonging to a PPE gene of Mycobacterium tuberculosis and its use in diagnosis of tuberculosis

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Variable expression patterns of Mycobacterium tuberculosis PE_PGRS genes: evidence that PE_PGRS16 and PE_PGRS26 are inversely regulated in vivo

1 reference

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1 reference

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Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Expression of the PE_PGRS 33 protein in Mycobacterium smegmatis triggers necrosis in macrophages and enhanced mycobacterial survival

1 reference

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Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis

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Natural transposon mutagenesis of clinical isolates of Mycobacterium tuberculosis: how many genes does a pathogen need?

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Regions of high antigenicity within the hypothetical PPE major polymorphic tandem repeat open-reading frame, Rv2608, show a differential humoral response and a low T cell response in various categories of patients with tuberculosis

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Transmission of tuberculosis in a high incidence urban community in South Africa

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1 reference

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Genetic requirements for mycobacterial survival during infection

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The complete genome sequence of Mycobacterium bovis

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Genes required for mycobacterial growth defined by high density mutagenesis

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1 reference

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Genomewide pattern of synonymous nucleotide substitution in two complete genomes of Mycobacterium tuberculosis

1 reference

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Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains

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Multiple Mycobacterium tuberculosis strains in early cultures from patients in a high-incidence community setting

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Expression, characterization and subcellular localization of the Mycobacterium tuberculosis PPE gene Rv1917c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Negligible genetic diversity of mycobacterium tuberculosis host immune system protein targets: evidence of limited selective pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

6 July 2018

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319526

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Disruption of coding regions by IS6110 insertion in Mycobacterium tuberculosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Differential expression of PE and PE_PGRS genes in Mycobacterium tuberculosis strains

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Gene expression diversity among Mycobacterium tuberculosis clinical isolates.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Regulation of the Mycobacterium tuberculosis PE/PPE genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Degradation-resistant protein domains limit host cell processing and immune detection of mycobacteria

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Genes under positive selection in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Defining putative T cell epitopes from PE and PPE families of proteins of Mycobacterium tuberculosis with vaccine potential

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Variation of the expression ofMycobacterium tuberculosis ppe44gene among clinical isolates

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

Comment on "The Origins of Genome Complexity"

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030593

21 January 2018

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis triggered by Rv1818c, a PE family gene from Mycobacterium tuberculosis is regulated by mitochondrial intermediates in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of mycobacterial PPE44 (Rv2770c) in Mycobacterium bovis BCG-infected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PGRS domain of Mycobacterium tuberculosis PE_PGRS Rv1759c antigen is an efficient subunit vaccine to prevent reactivation in a murine model of chronic tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RD1-encoded antigen Rv3872 of Mycobacterium tuberculosis as a potential candidate for serodiagnosis of tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22496726

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0030593

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...730593M

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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