(Q34230234)

English

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

scientific article published in September 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

Jinchun Zhou

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

James E Johnson

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Victor Ghetie

3

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8 November 2019

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1 September 2003

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8 November 2019

number of pages

13

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Journal of Molecular Biology

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Europe PubMed Central

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8 November 2019

332

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8 November 2019

4

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8 November 2019

901-913

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Distribution of immunoglobulin G receptors in the small intestine of the young rat

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

FcRn: the MHC class I-related receptor that is more than an IgG transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

FcRn-mediated transcytosis of immunoglobulin G in human renal proximal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Multiple roles for the major histocompatibility complex class I- related receptor FcRn

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Co-localization of the neonatal Fc gamma receptor and IgG in human placental term syncytiotrophoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Crystal structure of the complex of rat neonatal Fc receptor with Fc

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

An Fc receptor structurally related to MHC class I antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Stoichiometry of the interaction between the major histocompatibility complex-related Fc receptor and its Fc ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,)

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Sedimentation equilibrium analysis of recombinant mouse FcRn with murine IgG1.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Compensation for loss of ligand activity in surface plasmon resonance experiments.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Identification of critical IgG binding epitopes on the neonatal Fc receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Biochemical analysis of the N-glycosylation pathway in baculovirus-infected lepidopteran insect cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Intravascular metabolism of normal and mutant mouse immunoglobulin molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

The half-lives of serum immunoglobulins in adult mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Antibody framework residues affecting the conformation of the hypervariable loops

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900952-5

7 January 2021

Identifiers

10.1016/S0022-2836(03)00952-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12972260%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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