(Q34234705)

31 July 2017

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes (English)

1 reference

31 July 2017

0 references

Peter A van Veelen

6

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author name string

Gabrielle G M Pinkse

1

1 reference

31 July 2017

Odette H M Tysma

2

1 reference

31 July 2017

Cees A M Bergen

3

1 reference

31 July 2017

Michel G D Kester

4

1 reference

31 July 2017

Ferry Ossendorp

5

1 reference

31 July 2017

Bart Keymeulen

7

1 reference

31 July 2017

Danny Pipeleers

8

1 reference

31 July 2017

Jan W Drijfhout

9

1 reference

31 July 2017

Bart O Roep

10

1 reference

31 July 2017

language of work or name

English

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publication date

9 December 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

1 reference

31 July 2017

102

1 reference

31 July 2017

18425-18430

1 reference

31 July 2017

51

1 reference

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Endoplasmic reticulum stress and the development of diabetes: a review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Phenotypic analysis of antigen-specific T lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

A sensitive fluorometric assay for quantitatively measuring specific peptide binding to HLA class I and class II molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

The cleavage preference of the proteasome governs the yield of antigenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317949

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Identification of a -Cell-Specific HLA Class I Restricted Epitope in Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508621102

Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop

21 January 2018

1 reference

12 December 2020

Precursor frequencies of T-cells reactive to insulin in recent onset type 1 diabetes mellitus

1 reference

12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population. Childhood Diabetes in Finland (DiMe) Study Group

1 reference

12 December 2020

Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay

1 reference

12 December 2020

An HLA class I peptide-binding assay based on competition for binding to class I molecules on intact human B cells. Identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301

1 reference

12 December 2020

Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site

1 reference

12 December 2020

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects

1 reference

12 December 2020

Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies

1 reference

12 December 2020

Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0508621102

1 reference

31 July 2017

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1 reference

31 July 2017

1 reference