(Q34235121)

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Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.

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13 February 2020

Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827233%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

juvenile rheumatoid arthritis

1 reference

based on heuristic

inferred from title

pharmacogenomics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Halima Moncrieffe

1

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13 February 2020

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13 February 2020

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13 February 2020

7

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13 February 2020

8

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13 February 2020

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13 February 2020

Lucy R Wedderburn

12

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13 February 2020

Susan D Thompson

10

object named as

Susan D Thompson

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13 February 2020

author name string

Simona Ursu

3

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13 February 2020

Laura Kassoumeri

4

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13 February 2020

Angela Etheridge

5

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13 February 2020

David N Glass

9

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13 February 2020

publication date

1 November 2010

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13 February 2020

Pharmacogenetics and Genomics

1 reference

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13 February 2020

20

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13 February 2020

665-676

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13 February 2020

11

1 reference

Europe PubMed Central

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13 February 2020

GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Genome-wide QTL mapping for three traits related to teat number in a White Duroc x Erhualian pig resource population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Regulation of T-cell responses by PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Population genomics of human gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Methotrexate pharmacogenetics: the first step toward individualized therapy in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

How children's responses to drugs differ from adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Use of methotrexate in juvenile idiopathic arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

The British version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Peroxisome proliferator-activated receptors in inflammation control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Identification of a Zinc Finger Protein that Inhibits IL-2 Gene Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

6 July 2018

Glucose deprivation, oxidative stress and peroxisome proliferator-activated receptor-alpha (PPARA) cause peroxisome proliferation in preimplantation mouse embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Methotrexate improves the health-related quality of life of children with juvenile idiopathic arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Additional genetic susceptibility for rheumatoid arthritis telomeric of the DRB1 locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Identification of drug‐regulated genes in osteosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

Time to treatment as an important factor for the response to methotrexate in juvenile idiopathic arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963015

28 October 2018

A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary definition of improvement in juvenile arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An open access database of genome-wide association results

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the effects of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription regulatory polymorphism -43T>C in the 5'-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of health status, functional status, and quality of life in children with juvenile idiopathic arthritis: clinical science for the pediatrician

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The magnitude of early response to methotrexate therapy predicts long-term outcome of patients with juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcome in adults with juvenile idiopathic arthritis: a quality of life study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/20827233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/FPC.0B013E32833F2CD0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827233%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827233%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827233%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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