(Q34237470)

31 July 2017

title

Personalized oncology through integrative high-throughput sequencing: a pilot study (English)

1 reference

high-throughput sequencing

31 July 2017

main subject

1 reference

inferred from title

author

Shanker Kalyana-Sundaram

Shanker Kalyana-Sundaram

7

0 references

David C. Smith

David C Smith

20

0 references

Kenneth J. Pienta

Kenneth J Pienta

25

0 references

Lakshmi P Kunju

14

Lakshmi P Kunju

1 reference

31 July 2017

6

Xuhong Cao

1 reference

31 July 2017

4

Robert J Lonigro

1 reference

31 July 2017

Sameek Roychowdhury

1

1 reference

31 July 2017

Matthew K Iyer

2

1 reference

31 July 2017

Dan R Robinson

3

1 reference

31 July 2017

Yi-Mi Wu

5

1 reference

31 July 2017

Lee Sam

8

1 reference

31 July 2017

O Alejandro Balbin

9

1 reference

31 July 2017

Michael J Quist

10

1 reference

31 July 2017

Terrence Barrette

11

1 reference

31 July 2017

Jessica Everett

12

1 reference

31 July 2017

Javed Siddiqui

13

1 reference

31 July 2017

Nora Navone

15

1 reference

31 July 2017

John C Araujo

16

1 reference

31 July 2017

Patricia Troncoso

17

1 reference

31 July 2017

Christopher J Logothetis

18

1 reference

31 July 2017

Jeffrey W Innis

19

1 reference

31 July 2017

Christopher D Lao

21

1 reference

31 July 2017

Scott Y Kim

22

1 reference

31 July 2017

J Scott Roberts

23

1 reference

31 July 2017

Stephen B Gruber

24

1 reference

31 July 2017

Moshe Talpaz

26

1 reference

31 July 2017

Arul M Chinnaiyan

27

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 November 2011

1 reference

Science Translational Medicine

31 July 2017

published in

1 reference

31 July 2017

volume

3

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31 July 2017

issue

111

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31 July 2017

page(s)

111ra121

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High throughput interrogation of somatic mutations in high grade serous cancer of the ovary

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

ChimeraScan: a tool for identifying chimeric transcription in sequencing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Therapeutic strategies for targeting ras proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Integrated genomic analyses of ovarian carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

New strategies in metastatic melanoma: oncogene-defined taxonomy leads to therapeutic advances

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Use of whole-genome sequencing to diagnose a cryptic fusion oncogene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Comrad: detection of expressed rearrangements by integrated analysis of RNA-Seq and low coverage genome sequence data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Initial genome sequencing and analysis of multiple myeloma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

A protocol for genetic evaluation of patients with multiple colorectal adenomas and without evidence of APC gene mutation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Advances in understanding cancer genomes through second-generation sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

BRAF, a target in melanoma: implications for solid tumor drug development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

International network of cancer genome projects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Development of personalized tumor biomarkers using massively parallel sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

An oncogenic role for ETV1 in melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Complex landscapes of somatic rearrangement in human breast cancer genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Revving the Throttle on an oncogene: CDK8 takes the driver seat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Targeted capture and massively parallel sequencing of 12 human exomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Cell cycle, CDKs and cancer: a changing paradigm

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

PTEN and the PI3-kinase pathway in cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Unregulated smooth-muscle myosin in human intestinal neoplasia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

The protein kinase complement of the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Alterations of the PPP2R1B gene in human lung and colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3476478

Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers.

6 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003161

The Human Gene Mutation Database: 2008 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003161

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003161

Early accelerated approval for highly targeted cancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3003161

Do we have to change the way targeted drugs are developed?

21 January 2018

1 reference

12 December 2020

Tyrosine kinases as targets for cancer therapy

1 reference

12 December 2020

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

1 reference

12 December 2020

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

12 December 2020

BRAF Mutation in Papillary Thyroid Carcinoma

1 reference

12 December 2020

10.1126/SCITRANSLMED.3003161

Identifiers

DOI

1 reference

31 July 2017

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31 July 2017

1 reference