(Q34240091)

31 July 2017

1 reference

title

Transporters in African trypanosomes: role in drug action and resistance (English)

1 reference

31 July 2017

de Koning HP

1

1 reference

PubMed ID

11334936

31 July 2017

language of work or name

1 reference

1 May 2001

1 reference

International Journal for Parasitology

31 July 2017

1 reference

31 July 2017

31

1 reference

31 July 2017

512-522

1 reference

31 July 2017

5-6

1 reference

Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Resistance to DL-alpha-difluoromethylornithine by clinical isolates of Trypanosoma brucei rhodesiense. Role of S-adenosylmethionine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Trypanosome glucose transporters.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of the nitroimidazole drug megazol by African trypanosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pentamidine uptake in Leishmania donovani and Leishmania amazonensis promastigotes and axenic amastigotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Altered transport properties of pentamidine-resistant Leishmania donovani and L. amazonensis promastigotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Putrescine and spermidine transport in Leishmania.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Biochemical changes associated with alpha-difluoromethylornithine uptake and resistance in Trypanosoma brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Properties of melarsamine hydrochloride (Cymelarsan) in aqueous solution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Characterisation of pentamidine-resistant Trypanosoma brucei brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

In vitro drug sensitivity of Trypanosoma gambiense isolates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pharmacokinetic properties of the trypanocidal drug melarsoprol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by Trypanosoma brucei gambiense: a randomised trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Zoonotic infections in Nigeria: overview from a medical perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Clinical pharmacokinetics of suramin in patients with HTLV-III/LAV infection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Receptor-mediated endocytosis in the bloodstream form of Trypanosoma brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pentamidine Transport and Sensitivity inbrucei-Group Trypanosomes*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Hypoxanthine uptake through a purine-selective nucleobase transporter in Trypanosoma brucei brucei procyclic cells is driven by protonmotive force

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Purine nucleobase transport in bloodstream forms of Trypanosoma brucei brucei is mediated by two novel transporters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Characterization of a Nucleoside/Proton Symporter in ProcyclicTrypanosoma brucei brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake and mode of action of drugs used against sleeping sickness.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Drug resistance in Sudanese Trypanosoma evansi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Megazol combined with suramin: a chemotherapy regimen which reversed the CNS pathology in a model of human African trypanosomiasis in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of alpha-difluoromethylornithine by mouse fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of the trypanocidal drug suramin by bloodstream forms of Trypanosoma brucei and its effect on respiration and growth rate in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

A nitroimidazole-thiadiazole derivative with curative action in experimental Trypanosoma cruzi infections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Mel B in the treatment of human trypanosomiasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Some effects of pentamidine di-isethionate on Crithidia fasciculata

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Rapid and regulated degradation of ornithine decarboxylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Epidemiological relationships of Trypanosoma brucei stocks from south east Uganda: evidence for different population structures in human infective and non-human infective isolates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

The lesions produced in the central nervous system by certain organic arsenical compounds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to D,L-alpha-difluoromethylornithine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS : CHEMICAL SERIES. I. N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Physico-chemical properties of the trypanocidal drug melarsoprol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Investigations of the metabolites of the trypanocidal drug melarsoprol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pharmacokinetic investigations on diminazene and rolitetracycline in comparison to a combination of both

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Current situation of African trypanosomiasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Comparative pharmacokinetics of diminazene in noninfected Boran (Bos indicus) cattle and Boran cattle infected with Trypanosoma congolense

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Susceptibility of Ugandan Trypanosoma brucei rhodesiense isolated from man and animal reservoirs to diminazene, isometamidium and melarsoprol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Eflornithine concentrations in serum and cerebrospinal fluid of 63 patients treated for Trypanosoma brucei gambiense sleeping sickness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Derivation and characterization of a quinapyramine-resistant clone of Trypanosoma congolense

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Recent advances in the biochemistry of polyamines in eukaryotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

High-dose nifurtimox for arseno-resistant Trypanosoma brucei gambiense sleeping sickness: an open trial in central Zaire

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pharmacology of diminazene: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Cross-resistance associated with development of resistance to isometamidium in a clone of Trypanosoma congolense.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Blood-brain barrier damage in experimental African trypanosomiasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Induction of resistance to melarsenoxide cysteamine (Mel Cy) in Trypanosoma brucei brucei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Alteration to one of three adenosine transporters is associated with resistance to cymelarsan in Trypanosoma evansi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Uptake of NO-releasing drugs by the P2 nucleoside transporter in trypanosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Alterations in drug transport in resistant Trypanosoma congolense.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Reduced accumulation of isometamidium by drug-resistant Trypanosoma congolense

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Transport of isometamidium (Samorin) by drug-resistant and drug-sensitive Trypanosoma congolense

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

The uptake of the trypanocidal drug suramin in combination with low-density lipoproteins by Trypanosoma brucei and its possible mode of action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Pentamidine: Clinical pharmacologic correlations in man and mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Mechanisms of nucleobase transport in rabbit choroid plexus. Evidence for a Na(+)-dependent nucleobase transporter with broad substrate selectivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Modulation of mitochondrial electrical potential: a candidate mechanism for drug resistance in African trypanosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Drug resistance in trypanosomes: effects of metabolic inhibitiors, pH and oxidation-reduction potential on normal and resistant Trypanosoma rhodesiense

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Blood-brain barrier transport of reduced folic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

inferred from DOI database lookup

7 January 2021

based on heuristic

The treatment of human African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2801%2900167-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0020-7519(01)00167-9

1 reference

31 July 2017

1 reference

PubMed ID

11334936