(Q34240634)

31 July 2017

title

Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study (English)

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31 July 2017

18

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31 July 2017

Emma Hall

13

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Matthew R Sydes

object named as

Matthew R Sydes

12

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Søren M Bentzen

object named as

Søren M Bentzen

14

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Paul D P Pharoah

17

object named as

Paul D P Pharoah

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31 July 2017

10

Radka Platte

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31 July 2017

19

Catharine M L West

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31 July 2017

Gillian C Barnett

1

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31 July 2017

Charlotte E Coles

2

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31 July 2017

Rebecca M Elliott

3

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31 July 2017

Caroline Baynes

4

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31 July 2017

Craig Luccarini

5

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31 July 2017

Don Conroy

6

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31 July 2017

Jennifer S Wilkinson

7

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31 July 2017

Jonathan Tyrer

8

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31 July 2017

Vivek Misra

9

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31 July 2017

Sarah L Gulliford

11

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31 July 2017

David P Dearnaley

15

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31 July 2017

Neil G Burnet

16

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31 July 2017

publication date

12 December 2011

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Lancet Oncology Commission

31 July 2017

published in

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31 July 2017

volume

13

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31 July 2017

issue

1

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31 July 2017

page(s)

65-77

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Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues

31 July 2017

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Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology

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Genetic markers for prediction of normal tissue toxicity after radiotherapy

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Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype

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Genetic variation in normal tissue toxicity induced by ionizing radiation

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Radiosensitivity of human fibroblasts is associated with amino acid substitution variants in susceptible genes and correlates with the number of risk alleles.

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Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes

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Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy

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Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes.

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7 January 2021

IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.

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7 January 2021

Influence of multiple genetic polymorphisms on genitourinary morbidity after carbon ion radiotherapy for prostate cancer

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7 January 2021

Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial

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Implementing the UK Medical Research Council (MRC) RT01 trial (ISRCTN 47772397): methods and practicalities of a randomised controlled trial of conformal radiotherapy in men with localised prostate cancer.

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Dose-volume constraints to reduce rectal side effects from prostate radiotherapy: evidence from MRC RT01 Trial ISRCTN 47772397.

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7 January 2021

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7 January 2021

A tutorial on statistical methods for population association studies

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7 January 2021

The Cambridge Breast Intensity-modulated Radiotherapy Trial: patient- and treatment-related factors that influence late toxicity

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7 January 2021

Patient-to-patient variability in the expression of radiation-induced normal tissue injury

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7 January 2021

Radiobiological considerations in the design of clinical trials

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7 January 2021

Association between polymorphisms in the DNA repair genes, XRCC1, APE1, and XPD and acute side effects of radiotherapy in breast cancer patients

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7 January 2021

Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity

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7 January 2021

Haplotype-Based Analysis of Genes Associated With Risk of Adverse Skin Reactions After Radiotherapy in Breast Cancer Patients

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7 January 2021

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy.

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7 January 2021

Polymorphisms in genes related to oxidative stress (CAT, MnSOD, MPO, and eNOS) and acute toxicities from radiation therapy following lumpectomy for breast cancer

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7 January 2021

Functional consequences of ATM sequence variants for chromosomal radiosensitivity

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7 January 2021

Genetic predictors of long-term toxicities after radiation therapy for breast cancer

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7 January 2021

Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays

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7 January 2021

XPD polymorphisms: effects on DNA repair proficiency

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7 January 2021

Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series study

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7 January 2021

Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer

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7 January 2021

Germline glutathione S-transferase variants in breast cancer: Relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy

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7 January 2021

Gastrostomy in oropharyngeal cancer patients with ERCC4 (XPF) germline variants

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7 January 2021

Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.

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7 January 2021

Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity.

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7 January 2021

Analysis of variants in DNA damage signalling genes in bladder cancer

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7 January 2021

Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms

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7 January 2021

Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex.

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7 January 2021

Polymorphic MLH1 and risk of cancer after methylating chemotherapy for Hodgkin lymphoma.

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7 January 2021

No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study

1 reference

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7 January 2021

Association of single nucleotide polymorphisms in SOD2, XRCC1 and XRCC3 with susceptibility for the development of adverse effects resulting from radiotherapy for prostate cancer

1 reference

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7 January 2021

The late radiotherapy normal tissue injury phenotypes of telangiectasia, fibrosis and atrophy in breast cancer patients have distinct genotype-dependent causes

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7 January 2021

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Modulation of DNA damage/DNA repair capacity by XPC polymorphisms

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7 January 2021

Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations?

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7 January 2021

Influence of genetic polymorphisms on biomarkers of exposure and genotoxic effects in styrene-exposed workers

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7 January 2021

Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Influence of polymorphisms at loci encoding DNA repair proteins on cancer susceptibility and G2 chromosomal radiosensitivity

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Novel DNA sequence variants in the hHR21 DNA repair gene in radiosensitive cancer patients

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7 January 2021

The XRCC1 -77T->C variant: haplotypes, breast cancer risk, response to radiotherapy and the cellular response to DNA damage.

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7 January 2021

Evidence that individual variations in TP53 and CDKN1A protein responsiveness are related to inherent radiation sensitivity

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7 January 2021

The association between ATM D1853N polymorphism and breast cancer susceptibility: a meta-analysis

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7 January 2021

Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study

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7 January 2021

Why recent studies relating normal tissue response to individual radiosensitivity might have failed and how new studies should be performed

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7 January 2021

Individual variation and dose dependency in the progression rate of skin telangiectasia

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7 January 2021

How not to interpret a P value?

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7 January 2021

Association between common variation in 120 candidate genes and breast cancer risk

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

1 reference

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7 January 2021

Genome-wide association study identifies novel breast cancer susceptibility loci

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Genome-wide association study identifies five new breast cancer susceptibility loci

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Mutagen sensitivity has high heritability: evidence from a twin study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Genetic determination of chromosomal radiosensitivities in G0- and G2-phase human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

G(2) chromosomal radiosensitivity in Danish survivors of childhood and adolescent cancer and their offspring

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Heritability of susceptibility to ionizing radiation-induced apoptosis of human lymphocyte subpopulations

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Establishment of a Radiogenomics Consortium

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https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

Establishment of a radiogenomics consortium.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970302-3

7 January 2021

10.1016/S1470-2045(11)70302-3

Identifiers

DOI

1 reference

31 July 2017

1 reference