(Q34241383)

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Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

genome-wide association study

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pathway analysis

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based on heuristic

inferred from title

pancreatic cancer

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based on heuristic

inferred from title

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31 July 2017

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Anne Zeleniuch-Jacquotte

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Marie-Christine Boutron-Ruault

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Marie-Christine Boutron-Ruault

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Bas Bueno-de-Mesquita

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H Bas Bueno-de-Mesquita

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Demetrius Albanes

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Demetrius Albanes

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Patricia Hartge

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Patricia Hartge

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Charles Kooperberg

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Charles Kooperberg

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Laufey T. Amundadottir

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Laufey Amundadottir

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Anne Tjønneland

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Anne Tjønneland

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Geoffrey S Tobias

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Geoffrey S Tobias

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Kevin B. Jacobs

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Kevin B Jacobs

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Eric J Duell

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Sara H Olson

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Federico Canzian

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Federico Canzian

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Kay-Tee Khaw

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Stephen Chanock

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Stephen J Chanock

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Dimitris Trichopoulos

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Dimitrios Trichopoulos

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Göran Hallmans

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Göran Hallmans

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Wei Zheng

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Amy Hutchinson

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Xiao-Ou Shu

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David J. Hunter

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Susan E. Hankinson

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Mazda Jenab

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Jarmo Virtamo

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Rachael Z. Stolzenberg-Solomon

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Julie E. Buring

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Michael Goggins

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Edward L. Giovannucci

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Steven Gallinger

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Charles S. Fuchs

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Charles S Fuchs

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Andrea LaCroix

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Kari G Rabe

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Gloria M Petersen

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Brian M. Wolpin

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Michelle Cotterchio

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Elizabeth N Holly

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Elizabeth A Holly

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Alison P Klein

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Margaret T Mandelson

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Paige M Bracci

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Julie B. Mendelsohn

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Julie B Mendelsohn

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Harvey A. Risch

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Harvey A Risch

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Alpa V Patel

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J. Michael Gaziano

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J Michael Gaziano

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Kala Visvanathan

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Kala Visvanathan

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Judith Hoffman-Bolton

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Judith A Hoffman Bolton

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Robert R McWilliams

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Robert R McWilliams

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Eric J Jacobs

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Ilir Agalliu

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Joanne Watters

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Herbert Yu

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Peter Kraft

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Robert N. Hoover

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Robert N Hoover

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author name string

Donghui Li

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Kai Yu

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Li Jiao

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Xiaoqun Dong

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Bill Wheeler

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Myron Gross

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Kenneth Chang

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Robert C Kurtz

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language of work or name

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publication date

20 April 2012

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1384-1390

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31 July 2017

describes a project that uses

genome-wide association study

1 reference

based on heuristic

inferred from title

Selected medical conditions and risk of pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Analysing biological pathways in genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and cardiovascular health study).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Loss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Prioritizing GWAS results: A review of statistical methods and recommendations for their application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Loss of hepatocyte nuclear factor 1alpha function in human hepatocellular adenomas leads to aberrant activation of signaling pathways involved in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Pathway analysis by adaptive combination of P-values

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Nucleotide excision repair pathway polymorphisms and pancreatic cancer risk: evidence for role of MMS19L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Generation and regeneration of cells of the liver and pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

PDX-1 functions as a master factor in the pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Assembly of inflammation-related genes for pathway-focused genetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Transcription factors in pancreatic development. Animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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Immune surveillance of tumors

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6 July 2018

Common variants in HNF-1 alpha and risk of type 2 diabetes

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6 July 2018

The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405651

6 July 2018

Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies

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Lack of TCF2/vHNF1 in mice leads to pancreas agenesis

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Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development

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Bi-allelic inactivation of TCF1 in hepatic adenomas

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Fasting serum glucose level and cancer risk in Korean men and women

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Abnormal glucose metabolism and pancreatic cancer mortality

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Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability.

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21 January 2018

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21 January 2018

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28 October 2018

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28 October 2018

Mutation of TCF1 encoding hepatocyte nuclear factor 1α in gynecological cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS151

21 January 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying interacting SNPs using Monte Carlo logic regression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CARCIN/BGS151

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

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Europe PubMed Central

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31 July 2017

ResearchGate publication ID

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