(Q34241697)

31 July 2017

title

Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling (English)

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31 July 2017

3

Karen E Porter

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author name string

Nicola E Clarke

1

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31 July 2017

Martin J Fisher

2

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31 July 2017

Daniel W Lambert

4

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31 July 2017

Anthony J Turner

5

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31 July 2017

language of work or name

English

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publication date

16 April 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

4

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31 July 2017

page(s)

e34747

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

16 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration

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Not just angiotensinases: new roles for the angiotensin-converting enzymes

6 July 2018

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Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes.

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6 July 2018

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NADPH oxidases and angiotensin II receptor signaling

6 July 2018

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6 July 2018

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Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.

6 July 2018

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Modulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entry

6 July 2018

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Integrins as antimetastatic targets of RGD-independent snake venom components in liver metastasis [corrected].

6 July 2018

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Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain

6 July 2018

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Structural basis for ligand recognition by integrins

6 July 2018

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ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts.

6 July 2018

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Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury

6 July 2018

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Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold

6 July 2018

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Deficiency of beta1 integrins results in increased myocardial dysfunction after myocardial infarction

6 July 2018

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Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).

6 July 2018

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Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor

6 July 2018

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ACE2 gene expression is up-regulated in the human failing heart

6 July 2018

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ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis

6 July 2018

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Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

6 July 2018

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Temporal response and localization of integrins beta1 and beta3 in the heart after myocardial infarction: regulation by cytokines

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

6 July 2018

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Mediation of sperm-egg fusion: evidence that mouse egg alpha6beta1 integrin is the receptor for sperm fertilinbeta

6 July 2018

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Thrombin adhesive properties: induction by plasmin and heparan sulfate

6 July 2018

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Measurement of protein using bicinchoninic acid

6 July 2018

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A beta 1-integrin receptor for fibronectin in human kidney glomeruli

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion

6 July 2018

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Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

6 July 2018

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells.

6 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Angiotensin converting enzyme inhibitor prevents left ventricular remodelling after myocardial infarction in angiotensin II type 1 receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Beneficial effects of combination of ACE inhibitor and angiotensin II type 1 receptor blocker on cardiac remodeling in rat myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Myocardial infarction increases ACE2 expression in rat and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Functional angiotensin-converting enzyme 2 is expressed in human cardiac myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Development of potent and selective phosphinic peptide inhibitors of angiotensin-converting enzyme 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Chronic beta2-adrenergic receptor stimulation increases proliferation of human cardiac fibroblasts via an autocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat

21 January 2018

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034747

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Anti-migratory and anti-invasive effect of somatostatin in human neuroblastoma cells: involvement of Rac and MAP kinase activity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Expression of fibronectin, the integrin alpha 5, and alpha-smooth muscle actin in heart and lung development

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327712

Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction

28 October 2018

1 reference

12 December 2020

Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction

1 reference

12 December 2020

Monoclonal antibodies to denatured human ACE (CD 143), broad species specificity, reactivity on paraffin sections, and detection of subtle conformational changes in the C-terminal domain of ACE

1 reference

12 December 2020

Interaction of ACE2 and integrin beta1 in failing human heart

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0034747

Identifiers

DOI

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31 July 2017

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31 July 2017

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