(Q34242088)

31 July 2017

title

Different immunological mechanisms govern protection from experimental stroke in young and older mice with recombinant TCR ligand therapy (English)

1 reference

31 July 2017

1 reference

5

Halina Offner

1 reference

31 July 2017

Abby L Dotson

1

1 reference

31 July 2017

Wenbin Zhu

series ordinal

2

1 reference

31 July 2017

Nicole Libal

series ordinal

3

1 reference

31 July 2017

Nabil J Alkayed

series ordinal

4

1 reference

31 July 2017

language of work or name

1 reference

25 September 2014

1 reference

Frontiers in Cellular Neuroscience

31 July 2017

published in

1 reference

31 July 2017

volume

8

1 reference

31 July 2017

page(s)

284

1 reference

Recombinant T cell receptor ligand treatment improves neurological outcome in the presence of tissue plasminogen activator in experimental ischemic stroke

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Novel humanized recombinant T cell receptor ligands protect the female brain after experimental stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Phenotypic changes in immune cell subsets reflect increased infarct volume in male vs. female mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

A novel HLA-DRα1-MOG-35-55 construct treats experimental stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Leukocyte infiltration in experimental stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Adoptive regulatory T-cell therapy protects against cerebral ischemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Pivotal roles of monocytes/macrophages in stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Interleukin-17 in post-stroke neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Age and the metabolic syndrome as risk factors for ischemic stroke: improving preclinical models of ischemic stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

A transient decrease in spleen size following stroke corresponds to splenocyte release into systemic circulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Distinctive effects of T cell subsets in neuronal injury induced by cocultured splenocytes in vitro and by in vivo stroke in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Regulation of Antigen-Experienced T Cells: Lessons from the Quintessential Memory Marker CD44.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Homeostasis and function of regulatory T cells in aging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Recombinant T cell receptor ligands improve outcome after experimental cerebral ischemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Expansion of regulatory T cells in aged mice following influenza infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Middle cerebral artery occlusion model in rodents: methods and potential pitfalls

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Multifaceted regulation of T cells by CD44.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

RTL therapy for multiple sclerosis: a Phase I clinical study.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

CD44 and its role in inflammation and inflammatory diseases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Recombinant T cell receptor ligand treats experimental stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Tumor necrosis factor and stroke: role of the blood-brain barrier

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Inflammation in stroke and focal cerebral ischemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

1,026 experimental treatments in acute stroke

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

The influence of age on T cell generation and TCR diversity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4174768

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

IL-17 and IFN-gamma mRNA expression is increased in the brain and systemically after permanent middle cerebral artery occlusion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Regulatory T cells protect the brain after stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Regulatory T cells in ischemic stroke: helpful or hazardous?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

CD8 regulatory T cells: what's old is now new.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

The paradox role of regulatory T cells in ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Role of T lymphocytes and interferon-gamma in ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00284

Early T-cell activation in elderly humans

21 January 2018

1 reference

12 December 2020

Flow cytometric analysis of inflammatory cells in ischemic rat brain

1 reference

12 December 2020

Human leukocyte antigen-DRB1*1502 (DR2Dw12) transgene reduces incidence and severity of arthritis in mice

1 reference

12 December 2020

Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells

1 reference

12 December 2020

Design, engineering and production of functional single-chain T cell receptor ligands

1 reference

12 December 2020

Age-associated changes in interferon-gamma and interleukin-4 secretion by purified human CD4+ and CD8+ T cells

1 reference

12 December 2020

Con: Regulatory T cells are protective in ischemic stroke

1 reference

12 December 2020

Increased cytokine production in mononuclear cells of healthy elderly people

1 reference

12 December 2020

The increase of IFN-gamma production through aging correlates with the expanded CD8(+high)CD28(-)CD57(+) subpopulation

1 reference

12 December 2020

High accumulation of T regulatory cells prevents the activation of immune responses in aged animals

1 reference

12 December 2020

Experimental stroke induces massive, rapid activation of the peripheral immune system

1 reference

12 December 2020

Quantitative and qualitative changes in CD44 and MEL-14 expression by T cells in C57BL/6 mice during aging

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNCEL.2014.00284

1 reference

31 July 2017

1 reference

31 July 2017

1 reference