(Q34242199)

31 July 2017

title

Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist (English)

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31 July 2017

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ChEBI release 2020-05-28

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ChEBI release 2020-05-28

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Shirin Bruderer

1

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31 July 2017

Päivi Aänismaa

2

1 reference

31 July 2017

Marie-Claude Homery

3

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31 July 2017

Stephanie Häusler

4

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31 July 2017

Kyle Landskroner

5

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31 July 2017

Patricia N Sidharta

6

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31 July 2017

Alexander Treiber

7

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31 July 2017

Jasper Dingemanse

8

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31 July 2017

language of work or name

English

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publication date

22 December 2011

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31 July 2017

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31 July 2017

volume

14

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31 July 2017

issue

1

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31 July 2017

page(s)

68-78

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https://scigraph.springernature.com/pub.10.1208/s12248-011-9316-3

31 July 2017

exact match

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cites work

Macitentan: entry-into-humans study with a new endothelin receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Membrane transporters in drug development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Elucidating rifampin's inducing and inhibiting effects on glyburide pharmacokinetics and blood glucose in healthy volunteers: unmasking the differential effects of enzyme induction and transporter inhibition for a drug and its primary metabolite

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Update on rifampin and rifabutin drug interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Pharmacokinetic interactions with rifampicin : clinical relevance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Role of endothelin in cyclosporine-induced glomerular dysfunction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Endothelin receptor antagonism is protective in in vivo acute cyclosporine toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Effects of rifampicin (rifampin) on the pharmacokinetics and safety of ambrisentan in healthy subjects: a single-sequence, open-label study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Potential for pharmacokinetic interactions between ambrisentan and cyclosporine

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Dual effects of rifampin on the pharmacokinetics of atrasentan.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Inhibitory and inductive effects of rifampin on the pharmacokinetics of bosentan in healthy subjects.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Cyclosporin increases the exposure to tezosentan, an intravenous dual endothelin receptor antagonist

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Endothelin mediates the renal vasoconstriction induced by cyclosporine in the rat

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282010

Renal hemodynamics and pharmacokinetics of bosentan with and without cyclosporine A

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22189899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1208/S12248-011-9316-3

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Dimensions Publication ID

31 July 2017

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31 July 2017

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