(Q34243052)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anesthetics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

0 references

Manoel Arcisio-Miranda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Baron Chanda

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Yukiko Muroi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Sandipan Chowdhury

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

11 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

The Journal of General Physiology

15 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

541-554

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel

15 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

hERG gating microdomains defined by S6 mutagenesis and molecular modeling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Scalable molecular dynamics with NAMD

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Mechanism of local anesthetic drug action on voltage-gated sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Molecular action of lidocaine on the voltage sensors of sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Coupling between voltage sensors and activation gate in voltage-gated K+ channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Scanning the intracellular S6 activation gate in the shaker K+ channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Commentary: A revised view of local anesthetic action: what channel state is really stabilized?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Role of the S4 in cooperativity of voltage-dependent potassium channel activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Comparative protein modelling by satisfaction of spatial restraints

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Shaker potassium channel gating. I: Transitions near the open state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Lidocaine block of cardiac sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Kinetics and steady-state properties of the charged system controlling sodium conductance in the squid giant axon.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

QX-314 restores gating charge immobilization abolished by chloramine-T treatment in squid giant axons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Molecular basis of gating charge immobilization in Shaker potassium channels.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

The size of gating charge in wild-type and mutant Shaker potassium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Sodium inactivation mechanism modulates QX-314 block of sodium channels in squid axons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Interactions between quaternary lidocaine, the sodium channel gates, and tetrodotoxin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964522

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

6 July 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010438

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010438

Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010438

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010438

Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010438

Energetics of pore opening in a voltage-gated K(+) channel

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20937693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gating current in the membrane of nodes of Ranvier under conditions of linear alteration of the membrane potential

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20937693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1085/JGP.201010438

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20937693%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

20937693

1 reference