(Q43508073)

English

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

scientific article published in January 2001

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31 October 2019

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit (English)

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31 October 2019

transmembrane protein

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Vladimir Yarov-Yarovoy

1

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31 October 2019

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J Brown

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31 October 2019

E M Sharp

3

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31 October 2019

J J Clare

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31 October 2019

T Scheuer

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31 October 2019

W A Catterall

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31 October 2019

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1 January 2001

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31 October 2019

number of pages

8

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Journal of Biological Chemistry

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31 October 2019

276

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31 October 2019

1

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31 October 2019

20-27

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31 October 2019

Structure and function of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Auxiliary subunits of voltage-gated ion channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

1 reference

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21 January 2018

Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

1 reference

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21 January 2018

Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels

1 reference

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21 January 2018

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

1 reference

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21 January 2018

Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels

1 reference

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21 January 2018

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

1 reference

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21 January 2018

A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels

1 reference

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21 January 2018

Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel

1 reference

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21 January 2018

Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

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21 January 2018

Structural rearrangements underlying K+-channel activation gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Local anesthetic block of batrachotoxin-resistant muscle Na+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

1 reference

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21 January 2018

Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: symmetry relations and sequence comparisons between different species

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21 January 2018

Hydrophobic organization of membrane proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006992200

21 January 2018

The bacterial photosynthetic reaction center as a model for membrane proteins

1 reference

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21 January 2018

The anatomy and taxonomy of protein structure

1 reference

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21 January 2018

Structural basis of amino acid alpha helix propensity

1 reference

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21 January 2018

The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge

1 reference

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21 January 2018

Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy

1 reference

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21 January 2018

The lipid-protein interface of a Shaker K(+) channel

1 reference

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21 January 2018

A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel.

1 reference

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21 January 2018

alpha-helical structural elements within the voltage-sensing domains of a K(+) channel

1 reference

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21 January 2018

Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy

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21 January 2018

Lamotrigine versus other antiepileptic drugs: a star rating system is born

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21 January 2018

Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+ channels in rat hippocampal neurones

1 reference

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21 January 2018

State-dependent inhibition of Na+ currents by the neuroprotective agent 619C89 in rat hippocampal neurons and in a mammalian cell line expressing rat brain type IIA Na+ channels

1 reference

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21 January 2018

Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy

1 reference

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21 January 2018

A mutation in segment IVS6 disrupts fast inactivation of sodium channels

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M006992200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11024055%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11024055%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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