(Q34245299)

English

Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

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Stephen Henderson

object named as

Stephen Henderson

4

0 references

Clare L Bennett

object named as

Clare L Bennett

8

0 references

Ronjon Chakraverty

object named as

Ronjon Chakraverty

11

0 references

Gordon J. Freeman

9

object named as

Gordon J Freeman

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Barry Flutter

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Noha Edwards

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Farnaz Fallah-Arani

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Jian-Guo Chai

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Shivajanani Sivakumaran

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Sara Ghorashian

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Megan Sykes

10

1 reference

Europe PubMed Central

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31 July 2017

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publication date

18 October 2010

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Europe PubMed Central

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31 July 2017

Journal of Clinical Investigation

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Europe PubMed Central

PubMed publication ID

31 July 2017

120

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

3855-3868

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

1 reference

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6 July 2018

Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Early signals during CD8 T cell priming regulate the generation of central memory cells

1 reference

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6 July 2018

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation

1 reference

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6 July 2018

mTOR regulates memory CD8 T-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

1 reference

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6 July 2018

High antigen levels are the cause of T cell exhaustion during chronic viral infection

1 reference

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6 July 2018

Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection

1 reference

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6 July 2018

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Secondary replicative function of CD8+ T cells that had developed an effector phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Two host factors regulate persistence of H7-specific T cells injected in tumor-bearing mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Concurrent generation of effector and central memory CD8 T cells during vaccinia virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Lymphoid stroma in the initiation and control of immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

CD8 T cell dysfunction during chronic viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Experimental and clinical approaches for optimization of the graft-versus-leukemia effect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Factors governing the activation of adoptively transferred donor T cells infused after allogeneic bone marrow transplantation in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Host MHC class II+ antigen-presenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Human T cell responses against melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Host-reactive CD8+ memory stem cells in graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Peripheral tolerance of CD8 T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Central memory and effector memory T cell subsets: function, generation, and maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Graft-versus-leukemia reactions in allogeneic chimeras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

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6 July 2018

Cross-presentation, dendritic cells, tolerance and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

The molecular and functional characterization of a dominant minor H antigen, H60.

1 reference

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6 July 2018

Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Tolerance of CD8+ T cells developing in parent-->F1 chimeras prepared with supralethal irradiation: step-wise induction of tolerance in the intrathymic and extrathymic environments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

6 July 2018

Haploidentical stem cell transplantation after a reduced-intensity conditioning regimen for the treatment of advanced hematologic malignancies: posttransplantation CD8-depleted donor lymphocyte infusions contribute to improve T-cell recovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Different T cell receptor signals determine CD8+ memory versus effector development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

The race between infection and immunity: how do pathogens set the pace?

1 reference

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Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide

1 reference

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28 October 2018

HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism

1 reference

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28 October 2018

The host environment regulates the function of CD8+ graft-versus-host-reactive effector cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Adoptive immunotherapy of BCR-ABL-induced chronic myeloid leukemia-like myeloproliferative disease in a murine model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 specific T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras: possible implications for the graft-versus-host and graft-versus-leukemia reactivity of donor lymphocyte infusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964967

28 October 2018

NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graft-versus-leukemia and graft-versus-host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute graft-versus-host disease does not require alloantigen expression on host epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone marrow transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: extinction of graft-versus-leukemia effects after conversion to full donor chimerism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8+ T cell activation and cytolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graft-versus-leukemia effect using mixed allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of peripheral T cell tolerance induced by different doses of tolerogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differing phenotypes between intraepithelial and stromal lymphocytes in early-stage tongue cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive immunotherapy for relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: equal efficacy of lymphocytes from sibling and matched unrelated donors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20978352

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI41446

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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