(Q34246650)

31 July 2017

title

Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors (English)

1 reference

31 July 2017

Sheena Saayman

1

1 reference

31 July 2017

Patrick Arbuthnot

series ordinal

2

1 reference

31 July 2017

Marc S Weinberg

series ordinal

3

1 reference

31 July 2017

language of work or name

English

0 references

publication date

4 June 2010

1 reference

31 July 2017

published in

Nucleic Acids Research

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31 July 2017

volume

38

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31 July 2017

issue

19

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31 July 2017

page(s)

6652-6663

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Creative Commons Attribution-NonCommercial 2.5 Generic

31 July 2017

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-1 5' long terminal repeat

6 July 2018

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Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance

6 July 2018

1 reference

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Functional siRNA expression from transfected PCR products

6 July 2018

1 reference

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siRNA-mediated gene silencing in vitro and in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Gene silencing in mammalian cells by preformed small RNA duplexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Frequency of direct repeat deletion in a human immunodeficiency virus type 1 vector during reverse transcription in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

In situ demonstration of inhibitory effects of hammerhead ribozymes that are targeted to the hepatitis Bx sequence in cultured cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

High rate of recombination throughout the human immunodeficiency virus type 1 genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

Amplification of RNAi--targeting HLA mRNAs

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

Synthetic shRNAs as potent RNAi triggers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ460

Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965221

28 October 2018

Identifiers

DOI

10.1093/NAR/GKQ460

1 reference

31 July 2017

1 reference

31 July 2017

1 reference