(Q34246678)

31 July 2017

title

Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors (English)

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31 July 2017

Syed Ahmad

1

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31 July 2017

Mark A Hughes

series ordinal

2

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31 July 2017

Li-An Yeh

series ordinal

3

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31 July 2017

John E Scott

series ordinal

4

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31 July 2017

publication date

24 April 2012

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Journal of Biomolecular Screening

31 July 2017

published in

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31 July 2017

volume

17

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31 July 2017

issue

7

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31 July 2017

page(s)

957-965

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Topoisomerase I inhibitors: camptothecins and beyond

31 July 2017

cites work

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Pharmacogenetics of irinotecan metabolism and transport: an update

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Lessons learned from the irinotecan metabolic pathway

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Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

21 January 2018

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Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan

21 January 2018

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Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management

21 January 2018

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Hydrolysis of 4-methylumbelliferyl-beta-D-glucuronide in differing sample fractions of river waters and its implication for the detection of fecal pollution

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Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

21 January 2018

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A High Throughput Assay for Discovery of Bacterial β-Glucuronidase Inhibitors

21 January 2018

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A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

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A high-throughput screen for aggregation-based inhibition in a large compound library

21 January 2018

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The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours.

21 January 2018

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Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy

21 January 2018

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Relative activity of some inhibitors of mono-amine oxidase in potentiating the action of tryptamine in vitro and in vivo

21 January 2018

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MAO inhibitors: risks, benefits, and lore

21 January 2018

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Treatment of depression in cancer

21 January 2018

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New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors

21 January 2018

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Pharmacology of new antidepressants

21 January 2018

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Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography

21 January 2018

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Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1087057112444927

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31 July 2017

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