(Q34248754)

31 July 2017

title

Human herpesviruses-encoded dUTPases: a family of proteins that modulate dendritic cell function and innate immunity (English)

1 reference

31 July 2017

1 reference

1 reference

2

Ronald Glaser

1 reference

31 July 2017

Maria Eugenia Ariza

1

1 reference

31 July 2017

Marshall V Williams

series ordinal

3

1 reference

31 July 2017

publication date

26 September 2014

1 reference

Frontiers in Microbiology

31 July 2017

published in

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31 July 2017

volume

5

1 reference

31 July 2017

page(s)

504

1 reference

Cell death-associated molecular-pattern molecules: inflammatory signaling and control

31 July 2017

cites work

1 reference

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

6 July 2018

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IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

6 July 2018

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HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

6 July 2018

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Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cells

6 July 2018

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Modulation of B-cell exosome proteins by gamma herpesvirus infection

6 July 2018

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Abortive lytic reactivation of KSHV in CBF1/CSL deficient human B cell lines

6 July 2018

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Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy

6 July 2018

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Human herpesvirus 6A partially suppresses functional properties of DC without viral replication

6 July 2018

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Evidence for the role of Epstein Barr Virus infections in the pathogenesis of acute coronary events

6 July 2018

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Antibody to Epstein-Barr virus deoxyuridine triphosphate nucleotidohydrolase and deoxyribonucleotide polymerase in a chronic fatigue syndrome subset

6 July 2018

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Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy

6 July 2018

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Herpes simplex virus γ34.5 interferes with autophagosome maturation and antigen presentation in dendritic cells

6 July 2018

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Herpesviral infection and Toll-like receptor 2

6 July 2018

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Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44.

6 July 2018

1 reference

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Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB

6 July 2018

1 reference

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Effects of Epstein-Barr virus on the development of dendritic cells derived from cord blood monocytes: an essential role for apoptosis

6 July 2018

1 reference

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Latent Kaposi's sarcoma-associated herpesvirus infection of monocytes downregulates expression of adaptive immune response costimulatory receptors and proinflammatory cytokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

The anti-interferon activity of conserved viral dUTPase ORF54 is essential for an effective MHV-68 infection

6 July 2018

1 reference

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E4orf1: a novel ligand that improves glucose disposal in cell culture

6 July 2018

1 reference

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HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Recognition of herpesviruses by the innate immune system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

HIV-1 infection in the female reproductive tract: role of interactions between HIV-1 and genital epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human tumor virus utilizes exosomes for intercellular communication.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Activation of plasmacytoid dendritic cells by Kaposi's sarcoma-associated herpesvirus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Detection of HIV gp120 in plasma during early HIV infection is associated with increased proinflammatory and immunoregulatory cytokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Functional delivery of viral miRNAs via exosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

The EBV-encoded dUTPase activates NF-kappa B through the TLR2 and MyD88-dependent signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Functional Epstein-Barr virus reservoir in plasma cells derived from infected peripheral blood memory B cells

6 July 2018

1 reference

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Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Epstein-Barr virus induces MCP-1 secretion by human monocytes via TLR2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Epstein-Barr virus infection of Langerhans cell precursors as a mechanism of oral epithelial entry, persistence, and reactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

A new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Herpesvirus interference with major histocompatibility complex class II-restricted T-cell activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Innate immune recognition of viral infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

New genes from old: redeployment of dUTPase by herpesviruses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Viral replication-independent blockade of dendritic cell maturation and interleukin-12 production by human herpesvirus 6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Terminal differentiation into plasma cells initiates the replicative cycle of Epstein-Barr virus in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

6 July 2018

1 reference

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Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Varicella-zoster virus productively infects mature dendritic cells and alters their immune function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

6 July 2018

1 reference

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Expression of viral and human dUTPase in Epstein-Barr virus-associated diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Evolution of the dUTPase gene of mammalian and avian herpesviruses.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Phenotypic and functional alterations of dendritic cells induced by human herpesvirus 6 infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Productive infection of primary macrophages with human herpesvirus 7.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Varicella-zoster virus infection of human dendritic cells and transmission to T cells: implications for virus dissemination in the host

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Mature dendritic cells infected with herpes simplex virus type 1 exhibit inhibited T-cell stimulatory capacity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Infection of primary human monocytes by Epstein-Barr virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Evolution and horizontal transfer of dUTPase-encoding genes in viruses and their hosts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

"Hidden" dUTPase sequence in human immunodeficiency virus type 1 gp120

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Latent human herpesvirus 6 infection of human monocytes/macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

Crystal structure of a dUTPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176148

B-cell polyclonal activation and Epstein-Barr viral abortive lytic cycle are two key features in acute infectious mononucleosis

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Cutting edge: TLR2-mediated proinflammatory cytokine and chemokine production by microglial cells in response to herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

A human endogenous retrovirus K dUTPase triggers a TH1, TH17 cytokine response: does it have a role in psoriasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Evidence that the human cytomegalovirus 46-kDa UL72 protein is not an active dUTPase but a late protein dispensable for replication in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Localization of the Epstein-Barr virus protein LMP 1 to exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

EBV-encoded dUTPase induces immune dysregulation: Implications for the pathophysiology of EBV-associated disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Herpes simplex virus type I (HSV-1) replicates in mature dendritic cells but can only be transferred in a cell-cell contact-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) ORF54 encodes a functional dUTPase expressed in the lytic replication cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage-colony-stimulating factor and interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Transcriptional downregulation of DC-SIGN in human herpesvirus 6-infected dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Disruption of the varicella-zoster virus dUTPase and the adjacent ORF9A gene results in impaired growth and reduced syncytia formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

The monomeric dUTPase from Epstein-Barr virus mimics trimeric dUTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2014.00504

Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25309527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Introduction. dUTPases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25309527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FMICB.2014.00504

1 reference

31 July 2017

1 reference

31 July 2017

1 reference