(Q34249682)

31 July 2017

title

AT-1001: a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats (English)

1 reference

31 July 2017

0 references

Lawrence Toll

1

1 reference

31 July 2017

Nurulain T Zaveri

2

1 reference

31 July 2017

Willma E Polgar

3

1 reference

31 July 2017

Faming Jiang

4

1 reference

31 July 2017

Taline V Khroyan

5

1 reference

31 July 2017

Wei Zhou

6

1 reference

31 July 2017

Xinmin Simon Xie

7

1 reference

31 July 2017

Gregory B Stauber

8

1 reference

31 July 2017

Matthew R Costello

9

1 reference

31 July 2017

Frances M Leslie

10

1 reference

31 July 2017

language of work or name

English

0 references

publication date

25 January 2012

1 reference

31 July 2017

published in

Neuropsychopharmacology

1 reference

31 July 2017

volume

37

1 reference

31 July 2017

issue

6

1 reference

31 July 2017

page(s)

1367-1376

1 reference

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

18-Methoxycoronaridine blocks acquisition but enhances reinstatement of a cocaine place preference

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Genome-wide and candidate gene association study of cigarette smoking behaviors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on methamphetamine and sucrose self-administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Variants in nicotinic receptors and risk for nicotine dependence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Acetaldehyde, a major constituent of tobacco smoke, enhances behavioral, endocrine, and neuronal responses to nicotine in adolescent and adult rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Anti-addictive actions of an iboga alkaloid congener: a novel mechanism for a novel treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Human neuronal nicotinic receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Nicotine maintains robust self-administration in rats on a limited-access schedule

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

The neurobiology of tobacco addiction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

18-MC reduces methamphetamine and nicotine self-administration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Characterization of nicotinic agonist-induced [(3)H]dopamine release from synaptosomes prepared from four mouse brain regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Chronic nicotine differentially regulates alpha6- and beta3-containing nicotinic cholinergic receptors in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Common aspects of the action of nicotine and other drugs of abuse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Alpha3beta4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Blockade of nicotine self-administration with nicotinic antagonists in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2011.322

Specific activation of the alpha 7 nicotinic acetylcholine receptor by a quaternary analog of cocaine.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

The developmental increase in ACh current densities on rat sympathetic neurons correlates with changes in nicotinic ACh receptor alpha-subunit gene expression and occurs independent of innervation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327842

Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22278092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22278092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPP.2011.322

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference