(Q34251106)

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The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

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object named as

Jacek Zielonka

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PubMed publication ID

31 July 2017

5

object named as

Naoko Mizuno

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PubMed publication ID

31 July 2017

author name string

V Ashutosh Rao

1

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31 July 2017

Sarah R Klein

2

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31 July 2017

Spencer J Bonar

3

1 reference

Europe PubMed Central

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31 July 2017

Jennifer S Dickey

6

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Europe PubMed Central

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31 July 2017

Paul W Keller

7

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Europe PubMed Central

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31 July 2017

Joy Joseph

8

1 reference

Europe PubMed Central

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31 July 2017

Balaraman Kalyanaraman

9

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31 July 2017

Emily Shacter

10

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31 July 2017

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publication date

30 August 2010

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Europe PubMed Central

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31 July 2017

number of pages

13

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Journal of Biological Chemistry

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Europe PubMed Central

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31 July 2017

285

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Europe PubMed Central

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31 July 2017

45

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Europe PubMed Central

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31 July 2017

34447-34459

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Methods for detecting autophagy and determining autophagy-induced cell death.

1 reference

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Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q

1 reference

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6 July 2018

HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements

1 reference

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6 July 2018

OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma

1 reference

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6 July 2018

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

1 reference

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6 July 2018

Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

1 reference

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6 July 2018

Molecular mechanisms of Nrf2-mediated antioxidant response

1 reference

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6 July 2018

Targeting lipophilic cations to mitochondria.

1 reference

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A small molecule inhibitor of isoprenylcysteine carboxymethyltransferase induces autophagic cell death in PC3 prostate cancer cells

1 reference

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6 July 2018

Methods for assessing autophagy and autophagic cell death

1 reference

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6 July 2018

Mitochondria in cancer cells: what is so special about them?

1 reference

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6 July 2018

Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine.

1 reference

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6 July 2018

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

1 reference

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6 July 2018

Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers

1 reference

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6 July 2018

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

1 reference

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6 July 2018

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

1 reference

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6 July 2018

Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage

1 reference

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6 July 2018

Self-eating and self-killing: crosstalk between autophagy and apoptosis

1 reference

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Recent advances in high-pressure freezing: equipment- and specimen-loading methods

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How to interpret LC3 immunoblotting

1 reference

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6 July 2018

Selective degradation of mitochondria by mitophagy

1 reference

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6 July 2018

Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells

1 reference

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6 July 2018

Mitochondrial targeting of quinones: therapeutic implications.

1 reference

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Specific role of Chk1 phosphorylations in cell survival and checkpoint activation

1 reference

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Caspase inhibitors promote alternative cell death pathways

1 reference

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6 July 2018

Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells.

1 reference

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6 July 2018

Autophagy delays apoptotic death in breast cancer cells following DNA damage

1 reference

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6 July 2018

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

1 reference

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6 July 2018

Mitochondria: a target for cancer therapy

1 reference

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Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage

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Desferal inhibits breast tumor growth and does not interfere with the tumoricidal activity of doxorubicin

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Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

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Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.

1 reference

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Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

1 reference

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6 July 2018

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

1 reference

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Identifiers

10.1074/JBC.M110.133579

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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