(Q34258918)

1 August 2017

title

Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations (English)

1 reference

1 August 2017

Yongde Luo

1

1 reference

1 August 2017

Chaofeng Yang

2

1 reference

1 August 2017

Min Ye

3

1 reference

1 August 2017

Chengliu Jin

4

1 reference

1 August 2017

James L Abbruzzese

5

1 reference

1 August 2017

Mong-Hong Lee

6

1 reference

1 August 2017

Sai-Ching J Yeung

7

1 reference

1 August 2017

Wallace L McKeehan

8

1 reference

1 August 2017

publication date

25 November 2013

1 reference

1 August 2017

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1 August 2017

volume

1

1 reference

1 August 2017

issue

1

1 reference

1 August 2017

page(s)

21

1 reference

Creative Commons Attribution 2.0 Generic

1 August 2017

copyright license

start time

25 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/2049-3002-1-21

0 references

cites work

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Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress

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28 July 2018

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28 July 2018

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

28 July 2018

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Type 2 diabetes and obesity metabolic interactions: common factors for breast cancer risk and novel approaches to prevention and therapy

28 July 2018

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

28 July 2018

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Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Is growth hormone resistance/IGF-1 reduction good for you?

28 July 2018

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Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

28 July 2018

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Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation

28 July 2018

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Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

28 July 2018

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The FGF family: biology, pathophysiology and therapy

28 July 2018

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Nampt: linking NAD biology, metabolism and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

TIMP-1 as a tumor marker in breast cancer--an update

28 July 2018

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Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Liver-specific activities of FGF19 require Klotho beta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Klotho converts canonical FGF receptor into a specific receptor for FGF23

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Cancer's molecular sweet tooth and the Warburg effect.

28 July 2018

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Adipose tissue: from lipid storage compartment to endocrine organ

28 July 2018

1 reference

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Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

FGF-21 as a novel metabolic regulator

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Pituitary tumor-derived fibroblast growth factor receptor 4 isoform disrupts neural cell-adhesion molecule/N-cadherin signaling to diminish cell adhesiveness: a mechanism underlying pituitary neoplasia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Transforming growth factor alpha and mouse models of human breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

The heparan sulfate-fibroblast growth factor family: diversity of structure and function.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Cancer metabolism: fatty acid oxidation in the limelight

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

FGFR4 signaling is a necessary step in limb muscle differentiation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4178208

Functional FGFR4 Gly388Arg Polymorphism Predicts Prognosis in Lung Adenocarcinoma Patients

28 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F2049-3002-1-21

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24279986

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Murine FGFR-1 is required for early postimplantation growth and axial organization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24279986

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amino acid residues which distinguish the mitogenic potentials of two FGF receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24279986

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/2049-3002-1-21

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference