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Wnt signaling in cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
title
Wnt signaling in cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
author name string
Paul Polakis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
publication date
1 May 2012
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
published in
Cold Spring Harbor Perspectives in Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
volume
4
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
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Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome.
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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
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The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma
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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
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WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth
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Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
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Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation
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The internally truncated LRP5 receptor presents a therapeutic target in breast cancer
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Cancer stem cells: never Wnt away from the niche
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Deficiency of Mbd2 attenuates Wnt signaling
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A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
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Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma
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6 July 2018
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications
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6 July 2018
Wnt signalling and its impact on development and cancer
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6 July 2018
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling
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Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors
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Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
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Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
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siRNA-mediated beta-catenin knockdown in human hepatoma cells results in decreased growth and survival
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6 July 2018
The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
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6 July 2018
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
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6 July 2018
The many ways of Wnt in cancer
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6 July 2018
The consensus coding sequences of human breast and colorectal cancers
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6 July 2018
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis
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6 July 2018
Wnt signaling: is the party in the nucleus?
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Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
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TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription
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6 July 2018
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.
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6 July 2018
The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin
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6 July 2018
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
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6 July 2018
Wnt signalling in stem cells and cancer
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The links between axin and carcinogenesis
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An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
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6 July 2018
WNT and cyclooxygenase-2 cross-talk accelerates adenoma growth
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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
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Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.
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6 July 2018
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer
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6 July 2018
Wnt signaling and breast cancer
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6 July 2018
A protein knockdown strategy to study the function of beta-catenin in tumorigenesis
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6 July 2018
Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors
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6 July 2018
Repeated observation of breast tumor subtypes in independent gene expression data sets
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6 July 2018
Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells
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6 July 2018
Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.
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6 July 2018
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
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6 July 2018
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
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6 July 2018
COX selectivity and animal models for colon cancer
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6 July 2018
E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner
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6 July 2018
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6 July 2018
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
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6 July 2018
Apoptosis and APC in colorectal tumorigenesis
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6 July 2018
Suppression of intestinal neoplasia by DNA hypomethylation.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331705
retrieved
6 July 2018
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331705
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28 October 2018
beta-Catenin and p53 analyses of a breast carcinoma tissue microarray.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331705
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28 October 2018
Suppression of beta-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331705
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28 October 2018
Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of -Catenin, KRAS, and the Oncogenic Transcription Factor ITF2
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331705
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28 October 2018
Deficiency of Mbd2 suppresses intestinal tumorigenesis
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PubMed Central
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28 October 2018
AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22438566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22438566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22438566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Notch signals control the fate of immature progenitor cells in the intestine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22438566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/CSHPERSPECT.A008052
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
PMCID
3331705
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
PubMed ID
22438566
1 reference
stated in
Europe PubMed Central
PubMed ID
22438566
retrieved
1 August 2017
ResearchGate publication ID
221967462
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