(Q34265059)

1 August 2017

title

Lipocalin 2 is a regulator of macrophage polarization and NF-κB/STAT3 pathway activation (English)

1 reference

1 August 2017

0 references

1 reference

Hong Guo

1

1 reference

1 August 2017

Daozhong Jin

series ordinal

2

1 reference

1 August 2017

Xiaoli Chen

series ordinal

3

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1 August 2017

publication date

15 August 2014

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1 August 2017

published in

Molecular Endocrinology

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1 August 2017

volume

28

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1 August 2017

issue

10

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1 August 2017

page(s)

1616-1628

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Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanism

1 August 2017

cites work

1 reference

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Lipocalin 2 expression and secretion is highly regulated by metabolic stress, cytokines, and nutrients in adipocytes

6 July 2018

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STAT1, NF-κB and ERKs play a role in the induction of lipocalin-2 expression in adipocytes

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration

6 July 2018

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6 July 2018

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6 July 2018

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Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration

6 July 2018

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Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation

6 July 2018

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6 July 2018

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Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure

6 July 2018

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Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice

6 July 2018

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6 July 2018

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STATs in cancer inflammation and immunity: a leading role for STAT3

6 July 2018

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6 July 2018

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Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

6 July 2018

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Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

6 July 2018

1 reference

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Macrophage polarization in bacterial infections

6 July 2018

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Origin and physiological roles of inflammation

6 July 2018

1 reference

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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor gamma and nuclear factor-kappaB in macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

6 July 2018

1 reference

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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance

6 July 2018

1 reference

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Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

6 July 2018

1 reference

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

6 July 2018

1 reference

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Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

6 July 2018

1 reference

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Metabolic endotoxemia initiates obesity and insulin resistance

6 July 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

6 July 2018

1 reference

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Inflammation and metabolic disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Identification of common transcriptional regulatory elements in interleukin-17 target genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Inflammation, stress, and diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Obesity is associated with macrophage accumulation in adipose tissue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

A central role for JNK in obesity and insulin resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Lipocalins: unity in diversity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-alpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Secreted protein lipocalin-2 promotes microglial M1 polarization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179633

Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25127375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25127375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2014-1092

1 reference

1 August 2017

1 reference

1 August 2017

1 reference