(Q34268272)

1 August 2017

title

Analysis of the yield of phase II combination therapy trials in medical oncology (English)

1 reference

1 August 2017

Analysis of the Yield of Phase II Combination Therapy Trials in Medical Oncology (English)

1 reference

10.1158/1078-0432.CCR-10-0669

Crossref

DOI

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0669

12 July 2024

main subject

phase II clinical trial

0 references

4

Mark J Ratain

1 reference

1 August 2017

Christine Hudoba

2

1 reference

1 August 2017

Michael L. Maitland

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

12 July 2024

Kelly L. Snider

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

12 July 2024

language of work or name

English

0 references

publication date

13 September 2010

1 reference

full work available at URL

1 August 2017

https://aacrjournals.org/clincancerres/article-pdf/16/21/5296/1991790/5296.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

http://clincancerres.aacrjournals.org/cgi/content/abstract/16/21/5296

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837695/?tool=EBI

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837695/pdf/?tool=EBI

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://europepmc.org/articles/PMC2970723

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://europepmc.org/articles/PMC2970723?pdf=render

12 July 2024

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://doi.org/10.1158/1078-0432.ccr-10-0669

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837695

https://aacrjournals.org/clincancerres/article-pdf/16/21/5296/1991790/5296.pdf

12 July 2024

1 reference

10.1158/1078-0432.CCR-10-0669

Crossref

DOI

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0669

12 July 2024

published in

Clinical Cancer Research

1 reference

1 August 2017

volume

16

1 reference

1 August 2017

issue

21

1 reference

1 August 2017

page(s)

5296-5302

1 reference

The design of phase II clinical trials testing cancer therapeutics: consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Comparison of error rates in single-arm versus randomized phase II cancer clinical trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Novel designs and end points for phase II clinical trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Review of phase II trial designs used in studies of molecular targeted agents: outcomes and predictors of success in phase III.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Economics of new oncology drug development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Can the pharmaceutical industry reduce attrition rates?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Optimising the design of phase II oncology trials: the importance of randomisation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Analysis of phase II studies on targeted agents and subsequent phase III trials: what are the predictors for success?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970723

Current definitions of phases of investigation and the role of the FDA in the conduct of clinical trials

28 October 2018

1 reference

12 December 2020

Comparison of outcomes of phase II studies and subsequent randomized control studies using identical chemotherapeutic regimens

1 reference

12 December 2020

Phase II trials published in 2002: a cross-specialty comparison showing significant design differences between oncology trials and other medical specialties

1 reference

12 December 2020

Phase II trials in journal of clinical oncology

1 reference

12 December 2020

Phase I drug combination trial design: walking the tightrope

1 reference

12 December 2020

10.1158/1078-0432.CCR-10-0669

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference