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Identification of HIV-1 inhibitors targeting the nucleocapsid protein.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
title
Identification of HIV-1 inhibitors targeting the nucleocapsid protein
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
main subject
HIV
0 references
viral nucleocapsid
1 reference
based on heuristic
inferred from title
author
Max W Chang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
author name string
Sebastian Breuer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Jinyun Yuan
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Bruce E Torbett
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
language of work or name
English
0 references
publication date
24 May 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
published in
Journal of Medicinal Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
55
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
4968-4977
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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PubMed Central
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Properties and functions of the nucleocapsid protein in virus assembly
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Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein
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Targeting the viral nucleocapsid protein in anti-HIV-1 therapy.
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6 July 2018
Properties, functions, and drug targeting of the multifunctional nucleocapsid protein of the human immunodeficiency virus.
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6 July 2018
Single DNA molecule stretching measures the activity of chemicals that target the HIV-1 nucleocapsid protein.
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6 July 2018
Single point mutations in the zinc finger motifs of the human immunodeficiency virus type 1 nucleocapsid alter RNA binding specificities of the gag protein and enhance packaging and infectivity
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6 July 2018
Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.
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6 July 2018
The next generation of HIV/AIDS drugs: novel and developmental antiHIV drugs and targets
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6 July 2018
PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing
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Characterization of a putative alpha-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag.
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6 July 2018
Proline residues within spacer peptide p1 are important for human immunodeficiency virus type 1 infectivity, protein processing, and genomic RNA dimer stability
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6 July 2018
Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity
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6 July 2018
A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening
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6 July 2018
RNA is a structural element in retrovirus particles
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6 July 2018
NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition
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6 July 2018
NMR structure of stem-loop SL2 of the HIV-1 psi RNA packaging signal reveals a novel A-U-A base-triple platform
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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
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6 July 2018
A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity
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PubMed Central
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6 July 2018
The human immunodeficiency virus type 1 Gag polyprotein has nucleic acid chaperone activity: possible role in dimerization of genomic RNA and placement of tRNA on the primer binding site
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6 July 2018
Nucleomimetic strategy for the inhibition of HIV-1 nucleocapsid protein NCp7 activities
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6 July 2018
Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine.
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6 July 2018
A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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6 July 2018
Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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6 July 2018
HIV-1 nucleocapsid protein induces "maturation" of dimeric retroviral RNA in vitro
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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6 July 2018
Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.
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6 July 2018
Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS.
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6 July 2018
Retroviral RNA packaging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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6 July 2018
A cleavage enzyme-cytometric bead array provides biochemical profiling of resistance mutations in HIV-1 Gag and protease
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PubMed Central
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28 October 2018
In vitro identification and characterization of an early complex linking HIV-1 genomic RNA recognition and Pr55Gag multimerization
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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28 October 2018
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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28 October 2018
A Tryptophan-Rich Hexapeptide Inhibits Nucleic Acid Destabilization Chaperoned by the HIV-1 Nucleocapsid Proteinâ€
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499629
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28 October 2018
Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22587465
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Real experiences of uHTS: a prototypic 1536-well fluorescence anisotropy-based uHTS screen and application of well-level quality control procedures
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22587465
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Probing the topography of HIV-1 nucleocapsid protein with the alkylating agent N-ethylmaleimide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22587465
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/JM201442T
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMC publication ID
3499629
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
22587465
1 reference
stated in
Europe PubMed Central
PMC publication ID
3499629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22587465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
ResearchGate publication ID
224964842
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