(Q34270375)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Targeted immunotherapy of cancer with CAR T cells: achievements and challenges (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Grazyna Lipowska-Bhalla

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Robert E Hawkins

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Dominic G Rothwell

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

22 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

Cancer Immunology, Immunotherapy

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

953-962

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity

29 January 2020

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21 January 2018

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21 January 2018

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Muscle CARs and TcRs: turbo-charged technologies for the (T cell) masses

21 January 2018

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Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells.

21 January 2018

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Chimeric NK-receptor-bearing T cells mediate antitumor immunotherapy.

21 January 2018

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Chimeric NKG2D modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways

21 January 2018

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Cancer patient T cells genetically targeted to prostate-specific membrane antigen specifically lyse prostate cancer cells and release cytokines in response to prostate-specific membrane antigen

21 January 2018

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21 January 2018

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

21 January 2018

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21 January 2018

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Comparison of the TCR zeta-chain with the FcR gamma-chain in chimeric TCR constructs for T cell activation and apoptosis

21 January 2018

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Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma

21 January 2018

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21 January 2018

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Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

21 January 2018

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Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors

21 January 2018

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Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts.

21 January 2018

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Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation.

21 January 2018

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Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells

21 January 2018

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Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors

21 January 2018

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Immunotherapy of cancer using systemically delivered gene-modified human T lymphocytes

21 January 2018

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A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

21 January 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

21 January 2018

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Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

21 January 2018

1 reference

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In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)

21 January 2018

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

21 January 2018

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A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

21 January 2018

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Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo

21 January 2018

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

21 January 2018

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

21 January 2018

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

21 January 2018

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

21 January 2018

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Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias

21 January 2018

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Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

21 January 2018

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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor

21 January 2018

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Immune responses to transgene and retroviral vector in patients treated with ex vivo-engineered T cells

21 January 2018

1 reference

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Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice

21 January 2018

1 reference

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Immunobiology of allogeneic hematopoietic stem cell transplantation

21 January 2018

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Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.

21 January 2018

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Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.

21 January 2018

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Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice

21 January 2018

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In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells.

21 January 2018

1 reference

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10.1007/S00262-012-1254-0

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527245%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 January 2020

1007877133

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Fatcat ID

release_zvpm646m7jevlcdi7xopv26izq

1 reference

Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference