(Q34271965)

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Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling

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Europe PubMed Central

PubMed publication ID

1 August 2017

Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

apoptotic process

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ChEBI release 2020-05-28

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4

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Jai-Sing Yang

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1 August 2017

Jing-Gung Chung

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Jing-Gung Chung

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1 August 2017

5

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Hui-Ying Huang

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Europe PubMed Central

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1 August 2017

Shang-Ming Chiou

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object named as

Shang-Ming Chiou

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1 August 2017

3

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Su-Tso Yang

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Europe PubMed Central

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1 August 2017

author name string

Chiz-Hao Chiu

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1 August 2017

Chao-Lin Kuo

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1 August 2017

Po-Yuan Chen

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1 August 2017

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17 May 2012

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1 August 2017

Neurochemical Research

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1 August 2017

37

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1 August 2017

8

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1 August 2017

1790-1800

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PubMed publication ID

1 August 2017

Treatment of malignant glioma: a problem beyond the margins of resection

1 reference

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Malignant gliomas in adults

1 reference

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The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest

1 reference

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21 January 2018

Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways

1 reference

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21 January 2018

Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.

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Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival

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Grb2 SH2 domain-binding peptide analogs as potential anticancer agents

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In vitro genotoxicity of danthron and its potential mechanism

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21 January 2018

Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

1 reference

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21 January 2018

Danthron induces DNA damage and inhibits DNA repair gene expressions in GBM 8401 human brain glioblastoma multiforms cells

1 reference

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21 January 2018

Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells

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21 January 2018

Safrole induces apoptosis in human oral cancer HSC-3 cells.

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Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells

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DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway

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21 January 2018

Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.

1 reference

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21 January 2018

Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo

1 reference

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21 January 2018

Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells

1 reference

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21 January 2018

Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death

1 reference

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21 January 2018

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells

1 reference

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21 January 2018

Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice.

1 reference

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21 January 2018

Mechanism of cadmium induced apoptosis in the immunocyte.

1 reference

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21 January 2018

Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0792-3

21 January 2018

Mitochondria as therapeutic targets for cancer chemotherapy

1 reference

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21 January 2018

Mitochondrial medicine: pharmacological targeting of mitochondria in disease

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21 January 2018

Approaches to mitochondrially mediated cancer therapy

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21 January 2018

No death without life: vital functions of apoptotic effectors

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21 January 2018

Cinobufacini, an aqueous extract from Bufo bufo gargarizans Cantor, induces apoptosis through a mitochondria-mediated pathway in human hepatocellular carcinoma cells

1 reference

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21 January 2018

Garcinol inhibits cell growth in hepatocellular carcinoma Hep3B cells through induction of ROS-dependent apoptosis

1 reference

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21 January 2018

Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells

1 reference

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21 January 2018

Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

1 reference

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21 January 2018

Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

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Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of Bax and endonuclease G, and down-modulation of Bcl-XL involved in cardiotoxin III-induced apoptosis in K562 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gallic acid induces G₀/G₁ phase arrest and apoptosis in human leukemia HL-60 cells through inhibiting cyclin D and E, and activating mitochondria-dependent pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

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Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

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inferred from PubMed ID database lookup

Danthron alarm, FDA response: crucial OTC drug control

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses

1 reference

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The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Danthron (1,8-dihydroxyanthraquinone).

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Zanthoxylum ailanthoides Sieb and Zucc. extract inhibits growth and induces cell death through G2/M-phase arrest and activation of apoptotic signals in colo 205 human colon adenocarcinoma cells

1 reference

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Danthron inhibits the migration and invasion of human brain glioblastoma multiforme cells through the inhibition of mRNA expression of focal adhesion kinase, Rho kinases-1 and metalloproteinase-9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

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inferred from PubMed ID database lookup

Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Danthron inhibits murine WEHI-3 cells in vivo, and enhances macrophage phagocytosis and natural killer cell cytotoxic activity in leukemic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22592642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-012-0792-3

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Europe PubMed Central

PubMed publication ID

1 August 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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