(Q34273786)

1 August 2017

title

Dutasteride reduces alcohol's sedative effects in men in a human laboratory setting and reduces drinking in the natural environment (English)

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1 August 2017

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1 reference

1

Jonathan Covault

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1 August 2017

6

Henry R Kranzler

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1 August 2017

Timothy Pond

2

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1 August 2017

Richard Feinn

series ordinal

3

1 reference

1 August 2017

Albert J Arias

series ordinal

4

1 reference

1 August 2017

Cheryl Oncken

series ordinal

5

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1 August 2017

publication date

21 February 2014

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1 August 2017

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1 August 2017

volume

231

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1 August 2017

issue

17

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1 August 2017

page(s)

3609-3618

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A GABRA2 variant is associated with increased stimulation and 'high' following alcohol administration

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

GABRA2 markers moderate the subjective effects of alcohol.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Subjective and neural responses to intravenous alcohol in young adults with light and heavy drinking patterns

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Role of GABRA2 in moderating subjective responses to alcohol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3alpha-androstanediol and 17beta-estradiol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5alpha-reductase inhibitor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Neurosteroids: biochemistry and clinical significance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

The pharmacokinetic modelling of GI198745 (dutasteride), a compound with parallel linear and nonlinear elimination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

A model for the turnover of dihydrotestosterone in the presence of the irreversible 5 alpha-reductase inhibitors GI198745 and finasteride

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Experimental design in alcohol administration research: limitations and alternatives in the manipulation of dosage-set.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

A prospective randomized trial comparing finasteride to spironolactone in the treatment of hirsute women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

In vivo secretion of 3 alpha-hydroxy-5 alpha-pregnan-20-one, a potent anaesthetic steroid, by the adrenal gland of the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

5 alpha-metabolism in finasteride-treated subjects and male pseudohermaphrodites with inherited 5 alpha-reductase deficiency. A review.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Allelic and haplotypic association of GABRA2 with alcohol dependence

6 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

A new nomenclature for the aldo-keto reductase superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Biphasic alcohol response differs in heavy versus light drinkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Development and validation of the Biphasic Alcohol Effects Scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Subjective effects and changes in steroid hormone concentrations in humans following acute consumption of alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Alcohol intoxication increases allopregnanolone levels in male adolescent humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Alcohol Intoxication Increases Allopregnanolone Levels in Female Adolescent Humans

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181572

Decreased Alcohol Consumption Among Former Male Users of Finasteride with Persistent Sexual Side Effects: A Preliminary Report

28 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3487-4

Behavioral effects of 3 alpha-androstanediol. I: Modulation of sexual receptivity and promotion of GABA-stimulated chloride flux

21 January 2018

1 reference

12 December 2020

Comparison of finasteride versus flutamide in the treatment of hirsutism

1 reference

12 December 2020

Validation of the Sensation Scale, a measure of subjective physiological responses to alcohol

1 reference

12 December 2020

Effect of MK-906, a specific 5 alpha-reductase inhibitor, on serum androgens and androgen conjugates in normal men

1 reference

12 December 2020

Effects of finasteride (MK-906), a 5 alpha-reductase inhibitor, on circulating androgens in male volunteers

1 reference

12 December 2020

10.1007/S00213-014-3487-4

Identifiers

DOI

1 reference

Dimensions Publication ID

1 August 2017

0 references

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1 August 2017

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