(Q34274098)

English

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

prostate cancer

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Claudio R Santos

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Franziska Baenke

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

22 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Cancer Discovery

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

328-343

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Ultrahigh performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites

2 references

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

24 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1021/AC100101D

Cross-platform comparison of methods for quantitative metabolomics of primary metabolism

2 references

24 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1021/AC8022857

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Modulation of intracellular ROS levels by TIGAR controls autophagy

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Human placental fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase: its isozymic form, expression and characterization

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Single-vector inducible lentiviral RNAi system for oncology target validation

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Statistical methods for analysis of high-throughput RNA interference screens

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Cancer cell lines release glutamate into the extracellular environment.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

ATP citrate lyase inhibition can suppress tumor cell growth

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Tumor cell metabolism: cancer's Achilles' heel

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

PTEN-deficient cancers depend on PIK3CB.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Median absolute deviation to improve hit selection for genome-scale RNAi screens

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Brick by brick: metabolism and tumor cell growth

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Ras transformation requires metabolic control by 6-phosphofructo-2-kinase

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

A novel promoter sequence is involved in the oxidative stress-induced expression of the adult T-cell leukemia-derived factor (ADF)/human thioredoxin (Trx) gene

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Regulation of cancer cell metabolism

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells.

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

An integrated genomic analysis of human glioblastoma multiforme

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Citrate transport and metabolism in mammalian cells: prostate epithelial cells and prostate cancer

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

1 reference

24 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase

1 reference

27 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers

1 reference

27 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/2159-8290.CD-11-0234

Identifiers

10.1158/2159-8290.CD-11-0234

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22576210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34274098&oldid=1787823855"