(Q55462757)

12 July 2018

title

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival. (English)

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12 July 2018

author

Marc Zapatka

5

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12 July 2018

Bernhard Radlwimmer

15

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12 July 2018

author name string

V Goidts

1

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12 July 2018

J Bageritz

2

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12 July 2018

L Puccio

3

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12 July 2018

S Nakata

4

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12 July 2018

S Barbus

6

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12 July 2018

G Toedt

7

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12 July 2018

B Campos

8

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12 July 2018

A Korshunov

9

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12 July 2018

S Momma

10

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12 July 2018

E Van Schaftingen

11

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12 July 2018

G Reifenberger

12

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12 July 2018

C Herold-Mende

13

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12 July 2018

P Lichter

14

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12 July 2018

language of work or name

English

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publication date

7 November 2011

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12 July 2018

published in

Oncogene

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12 July 2018

volume

31

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12 July 2018

issue

27

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12 July 2018

page(s)

3235-3243

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12 July 2018

https://scigraph.springernature.com/pub.10.1038/onc.2011.490

exact match

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cites work

Cancer stem cells and oncology therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Differentiation therapy exerts antitumor effects on stem-like glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Chemotherapy resistance of glioblastoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Probing the human kinome for kinases involved in pancreatic cancer cell survival and gemcitabine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Cancer cell metabolism: Warburg and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Hypoxia-inducible factors, stem cells, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Expression of hypoxia-inducible genes in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2, 6-bisphosphatase gene (PFKFB3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Metabolic modulation of glioblastoma with dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Applying the principles of stem-cell biology to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Cancer stem cell-directed therapies: recent data from the laboratory and clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Chemoradiotherapy in malignant glioma: standard of care and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

21 January 2018

Brain tumour stem cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.490

21 January 2018

Identifiers

DOI

10.1038/ONC.2011.490

1 reference

12 July 2018

Dimensions Publication ID

1029727370

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Fatcat ID

release_j2scpk5safa2pgzvpyrstarlxi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j2scpk5safa2pgzvpyrstarlxi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22056879

1 reference

12 July 2018