(Q54673894)

2 June 2018

title

Molecular signatures classify astrocytic gliomas by IDH1 mutation status. (English)

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2 June 2018

author

Bernhard Radlwimmer

17

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2 June 2018

Andreas von Deimling

12

object named as

Andreas von Deimling

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2 June 2018

16

Guido Reifenberger

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2 June 2018

3

Marietta Wolter

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2 June 2018

4

Jörg Felsberg

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2 June 2018

15

Peter Lichter

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2 June 2018

author name string

Grischa Toedt

1

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2 June 2018

Sebastian Barbus

2

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2 June 2018

Björn Tews

5

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2 June 2018

Frederic Blond

6

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2 June 2018

Michael C Sabel

7

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2 June 2018

Stefanie Hofmann

8

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2 June 2018

Natalia Becker

9

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2 June 2018

Christian Hartmann

10

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2 June 2018

Hiroko Ohgaki

11

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2 June 2018

Otmar D Wiestler

13

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2 June 2018

Meinhard Hahn

14

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2 June 2018

language of work or name

English

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publication date

1 March 2011

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2 June 2018

International Journal of Cancer

published in

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2 June 2018

volume

128

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2 June 2018

page(s)

1095-1103

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2 June 2018

issue

5

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2 June 2018

Genetic pathways to primary and secondary glioblastoma

cites work

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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Analysis of the IDH1 codon 132 mutation in brain tumors

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Gene expression profiling of gliomas strongly predicts survival

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology.

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

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Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

21 January 2018

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IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

21 January 2018

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IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

21 January 2018

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Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

21 January 2018

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

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Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

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Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

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IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas

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The prognostic relevance of molecular alterations in glioblastomas for patients age < 50 years.

21 January 2018

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A new role for Nogo as a regulator of vascular remodeling

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Neuronal Nogo-A modulates growth cone motility via Rho-GTP/LIMK1/cofilin in the unlesioned adult nervous system

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Genetic pathways to glioblastomas

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DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

21 January 2018

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A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors

21 January 2018

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A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.

21 January 2018

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Keratinocyte growth factor: effects on keratinocytes and mechanisms of action

21 January 2018

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Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.25448

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2 June 2018

PubMed ID

20473936

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2 June 2018