(Q43228472)

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Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

scientific article published on 7 December 2009

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scholarly article

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13 February 2020

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation (English)

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13 February 2020

apoptotic process

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based on heuristic

inferred from title

Sandrine Marchetti

5

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13 February 2020

Cristina Muñoz-Pinedo

6

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13 February 2020

Patrick Auberger

7

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author name string

L A Pradelli

1

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M Bénéteau

2

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C Chauvin

3

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M A Jacquin

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M Pende

8

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J-E Ricci

9

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7 December 2009

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13 February 2020

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13 February 2020

29

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11

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1641-1652

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13 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2009.448

0 references

The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells

1 reference

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The survival kinases Akt and Pim as potential pharmacological targets

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Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst

1 reference

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Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario

1 reference

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Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

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Seeking a home for a PET, part 3: Emerging applications of positron emission tomography imaging in the management of patients with lung cancer

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Metformin and reduced risk of cancer in diabetic patients

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21 January 2018

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

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21 January 2018

Molecular imaging of cancer with positron emission tomography

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Defining the role of mTOR in cancer

1 reference

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21 January 2018

Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

1 reference

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21 January 2018

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

1 reference

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21 January 2018

The promise of TRAIL--potential and risks of a novel anticancer therapy

1 reference

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21 January 2018

TRAIL and cancer therapy.

1 reference

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21 January 2018

Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

AMP-activated protein kinase signaling in metabolic regulation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

T and B leukemic cell lines exhibit different requirements for cell death: correlation between caspase activation, DFF40/DFF45 expression, DNA fragmentation and apoptosis in T cell lines but not in Burkitt's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

1 reference

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21 January 2018

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

mTORC1 promotes survival through translational control of Mcl-1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

mir-29 regulates Mcl-1 protein expression and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Targeting death-inducing receptors in cancer therapy

1 reference

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21 January 2018

Growth factors can influence cell growth and survival through effects on glucose metabolism

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Glucose depletion enhances the anti-tumor effect of TNF.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Dissecting eIF4E action in tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.448

21 January 2018

Identifiers

10.1038/ONC.2009.448

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966861%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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1 reference

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13 February 2020

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