(Q43873071)

27 November 2017

Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway (English)

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27 November 2017

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Seon Young Nam

1

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27 November 2017

Andrew A Amoscato

series ordinal

2

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27 November 2017

Yong J Lee

series ordinal

3

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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27 November 2017

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27 November 2017

21

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27 November 2017

337-346

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27 November 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205068

27 November 2017

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cites work

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Apoptosis control by death and decoy receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Caspases: the executioners of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

A novel receptor for Apo2L/TRAIL contains a truncated death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

The receptor for the cytotoxic ligand TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

The role of phosphoinositide 3-kinase lipid products in cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Bcl-2 oncoprotein protects the human prostatic carcinoma cell line PC3 from TRAIL-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

FAP-1: a protein tyrosine phosphatase that associates with Fas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Ion channel activity of the BH3 only Bcl-2 family member, BID.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Identification of Raf-1 Ser621 kinase activity from NIH 3T3 cells as AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Mass spectrometric identification of increased C16 ceramide levels during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

The relevance of tumour pH to the treatment of malignant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Identification and characterization of a new member of the TNF family that induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Ceramide Induces CytochromecRelease from Isolated Mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

Apoptosis-induced by TRAIL AND TNF-alpha in human multiple myeloma cells is not blocked by BCL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

How TRAIL kills cancer cells, but not normal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Mohs surgery for nonagenerians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Role of dietary factors in cell replication and colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205068

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205068

1 reference

Dimensions Publication ID

27 November 2017

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1 reference