(Q34275603)

English

Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

object named as

Xuejun Wang

9

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Jeffery D. Molkentin

object named as

Jeffery D Molkentin

8

0 references

author name string

Mingxin Tang

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Jie Li

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Wei Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Huabo Su

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Qiangrong Liang

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Zongwen Tian

6

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Kathleen M Horak

7

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

2 July 2010

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Cardiovascular Research

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

88

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

424-433

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Markers of autophagy are downregulated in failing human heart after mechanical unloading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Functional alterations of cardiac proteasomes under physiological and pathological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Proteasome inhibitors and cardiac cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Regulation of the stability and transcriptional activity of NFATc4 by ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Alpha B-crystallin suppresses pressure overload cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

The heart of autophagy: deconstructing cardiac proteotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

The ubiquitin-proteasome system in cardiac dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Acute severe cardiac failure in a myeloma patient due to proteasome inhibitor bortezomib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Autophagy is an adaptive response in desmin-related cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Protein quality control and degradation in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Regulation of cardiac hypertrophy by intracellular signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Impairment of the ubiquitin-proteasome system in desminopathy mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Structural basis of ventricular remodeling: role of the myocyte.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Regulation of calcineurin through transcriptional induction of the calcineurin A beta promoter in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

6 July 2018

The proteasome inhibitor bortezomib aggravates renal ischemia-reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Suppression of cardiomyocyte hypertrophy by inhibition of the ubiquitin-proteasome system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

In situ dynamically monitoring the proteolytic function of the ubiquitin-proteasome system in cultured cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Mouse model of desmin-related cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972684

28 October 2018

Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Storage of phosphorylated desmin in a familial myopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted proteolysis sustains calcineurin activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unexpected cardiotoxicity in haematological bortezomib treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20601385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CVR/CVQ217

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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