(Q34276376)

1 August 2017

title

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model (English)

1 reference

1 August 2017

0 references

1 reference

Heng Du

1

1 reference

1 August 2017

Lan Guo

2

1 reference

1 August 2017

Shiqiang Yan

3

1 reference

1 August 2017

Alexander A Sosunov

4

1 reference

1 August 2017

Guy M McKhann

5

1 reference

1 August 2017

Shirley ShiDu Yan

6

1 reference

1 August 2017

language of work or name

English

0 references

publication date

11 October 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

1 August 2017

volume

107

1 reference

1 August 2017

issue

43

1 reference

1 August 2017

page(s)

18670-18675

1 reference

Mitochondrial medicine for neurodegenerative diseases

1 August 2017

cites work

1 reference

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6 July 2018

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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

6 July 2018

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

6 July 2018

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Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

6 July 2018

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

6 July 2018

1 reference

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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

6 July 2018

1 reference

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Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation

6 July 2018

1 reference

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Endophilin I expression is increased in the brains of Alzheimer disease patients

6 July 2018

1 reference

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Amyloid-beta-induced mitochondrial dysfunction

6 July 2018

1 reference

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Interaction of amyloid binding alcohol dehydrogenase/Abeta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model

6 July 2018

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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

6 July 2018

1 reference

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Mitochondria and neurotransmission: evacuating the synapse

6 July 2018

1 reference

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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

6 July 2018

1 reference

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The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

6 July 2018

1 reference

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Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

6 July 2018

1 reference

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A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

6 July 2018

1 reference

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Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Abundant type 10 17 beta-hydroxysteroid dehydrogenase in the hippocampus of mouse Alzheimer's disease model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

6 July 2018

1 reference

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Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

ATP mediates fast synaptic transmission in mammalian neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Further observations on hippocampal neurons in dispersed cell culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Role of cyclophilin D in the resistance of brain mitochondria to the permeability transition.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Mitochondrial trafficking to synapses in cultured primary cortical neurons.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Intraneuronal Abeta42 accumulation in Down syndrome brain.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

beta-Amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

N-acetylcysteine protects against age-related increase in oxidized proteins in mouse synaptic mitochondria.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972922

The role of mitochondria in presynaptic calcium handling at a ribbon synapse

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20937894

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alzheimer's APP mangles mitochondria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20937894

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1006586107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference