(Q34276711)

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Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by alpha-crystallin-B.

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Europe PubMed Central

PubMed publication ID

1 August 2017

Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by alpha-crystallin-B. (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

endoplasmic reticulum

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11

object named as

Andrew Emili

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1 August 2017

4

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Ruth Isserlin

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1 August 2017

author name string

Nicolas Bousette

1

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1 August 2017

Shaan Chugh

2

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1 August 2017

Vincent Fong

3

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1 August 2017

Kyoung-Han Kim

5

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1 August 2017

Allen Volchuk

6

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Europe PubMed Central

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1 August 2017

Peter H Backx

7

1 reference

Europe PubMed Central

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1 August 2017

Peter Liu

8

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1 August 2017

Thomas Kislinger

9

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Europe PubMed Central

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1 August 2017

David H MacLennan

10

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1 August 2017

Anthony O Gramolini

12

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1 August 2017

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publication date

11 October 2010

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Europe PubMed Central

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1 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

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1 August 2017

107

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Europe PubMed Central

PubMed publication ID

1 August 2017

43

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Europe PubMed Central

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1 August 2017

18481-18486

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Europe PubMed Central

PubMed publication ID

1 August 2017

MicroRNAs add a new dimension to cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: a novel mechanism for progressive cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Large-scale characterization and analysis of the murine cardiac proteome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Cross-talk between calcineurin/NFAT and Jak/STAT signalling induces cardioprotective alphaB-crystallin gene expression in response to hypertrophic stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Over-expression of Reticulon 3 (RTN3) enhances TRAIL-mediated apoptosis via up-regulation of death receptor 5 (DR5) and down-regulation of c-FLIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Deaths: final data for 2005.

1 reference

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6 July 2018

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

1 reference

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6 July 2018

Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Endoplasmic reticulum stress: cell life and death decisions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Phospholamban: a crucial regulator of cardiac contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Energy metabolism in the hypertrophied heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Expression profiling of cardiac genes in human hypertrophic cardiomyopathy: insight into the pathogenesis of phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

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Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

6 July 2018

Time-dependent systolic and diastolic function in mice overexpressing calcineurin

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy

1 reference

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21 January 2018

A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Analyzing the cardiac muscle proteome by liquid chromatography-mass spectrometry-based expression proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

28 October 2018

Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972971

28 October 2018

Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: Co-operation with Src tyrosine kinase

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013555107

21 January 2018

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptotic activity of Bcl-2 is enhanced by its interaction with RTN3

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and distribution of atrial natriuretic peptide in human hypertrophic ventricle of hypertensive hearts and hearts with hypertrophic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heart block in mice overexpressing calcineurin but not NF-AT3

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1013555107

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2010PNAS..10718481B

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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