(Q34278037)

1 August 2017

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title

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway (English)

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1 August 2017

Brunet A

1

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1 August 2017

Datta SR

series ordinal

2

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1 August 2017

Greenberg ME

series ordinal

3

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1 August 2017

publication date

1 June 2001

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Current Opinion in Neurobiology

1 August 2017

published in

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1 August 2017

volume

11

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1 August 2017

issue

3

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1 August 2017

page(s)

297-305

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https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

1 August 2017

1 reference

7 January 2021

TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

1 reference

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Signaling--2000 and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The development and therapeutic potential of protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt regulates cell survival and apoptosis at a postmitochondrial level

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Rsk1 mediates a MEK-MAP kinase cell survival signal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Calcium signaling in neurons: molecular mechanisms and cellular consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2800%2900211-7

7 January 2021

10.1016/S0959-4388(00)00211-7

Identifiers

DOI

1 reference

release_e7aeygyf3rau7cusc3zk5b7vlu

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e7aeygyf3rau7cusc3zk5b7vlu

24 November 2022

mapped directly with Wikidata item

1 reference