(Q34278937)

1 August 2017

title

Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets (English)

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G protein-coupled receptor

1 August 2017

main subject

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1

Vadim Cherezov

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1 August 2017

2

Enrique Abola

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1 August 2017

Raymond C Stevens

3

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1 August 2017

language of work or name

English

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publication date

1 January 2010

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Methods in Molecular Biology

1 August 2017

published in

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1 August 2017

volume

654

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1 August 2017

page(s)

141-168

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Crystallizing membrane proteins using lipidic mesophases

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization

6 July 2018

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Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Crystallizing membrane proteins for structure determination: use of lipidic mesophases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Topology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptors

6 July 2018

1 reference

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

6 July 2018

1 reference

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Crystal structure of opsin in its G-protein-interacting conformation

6 July 2018

1 reference

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New lipid family that forms inverted cubic phases in equilibrium with excess water: molecular structure-aqueous phase structure relationship for lipids with 5,9,13,17-tetramethyloctadecyl and 5,9,13,17-tetramethyloctadecanoyl chains

6 July 2018

1 reference

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Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor

6 July 2018

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

6 July 2018

1 reference

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A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

6 July 2018

1 reference

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Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

6 July 2018

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

6 July 2018

1 reference

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

6 July 2018

1 reference

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Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance

6 July 2018

1 reference

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The 7 TM G-protein-coupled receptor target family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Detergents Destabilize the Cubic Phase of Monoolein: Implications for Membrane Protein Crystallization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Crystallization screens: compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Crystal structure of rhodopsin: A G protein-coupled receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Membrane protein crystallization in lipidic mesophases: detergent effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Structure of bacteriorhodopsin at 1.55 A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Lipidic cubic phases: a novel concept for the crystallization of membrane proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Theoretical analysis of fluorescence photobleaching recovery experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

A monoclonal antibody for G protein-coupled receptor crystallography

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Membrane-protein stability in a phospholipid-based crystallization medium.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Trace fluorescent labeling for high-throughput crystallography

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Rational design of lipid for membrane protein crystallization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

The effect of increasing concentrations of precipitating salts used to crystallize proteins on the structure of the lipidic Q224 cubic phase.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973844

Enzymic release of crystals from lipidic cubic phases

28 October 2018

1 reference

12 December 2020

The phase diagram of the monoolein/water system: metastability and equilibrium aspects

1 reference

12 December 2020

Room to move: crystallizing membrane proteins in swollen lipidic mesophases

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

A simple mechanical mixer for small viscous lipid-containing samples

1 reference

12 December 2020

10.1007/978-1-60761-762-4_8

Identifiers

DOI

1 reference

1 August 2017

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1 August 2017

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