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Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.
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Europe PubMed Central
PMC publication ID
133844
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
title
Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA
(English)
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stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
leukemia
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inferred from title
guanine
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author
David Siderovski
series ordinal
2
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Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
Michelle A Booden
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Channing J Der
series ordinal
3
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Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
language of work or name
English
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publication date
1 June 2002
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stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Molecular and Cellular Biology
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stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
22
1 reference
stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
12
1 reference
stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
4053-4061
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stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.
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Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
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Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho
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Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.
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Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins
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Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia
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Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member
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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho
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6 July 2018
Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13
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6 July 2018
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6 July 2018
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13
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p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13
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6 July 2018
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6 July 2018
The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.
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6 July 2018
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis
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6 July 2018
Dbl family proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844
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6 July 2018
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
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6 July 2018
Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein
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6 July 2018
Identification of a novel guanine nucleotide exchange factor for the Rho GTPase
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6 July 2018
Heterotrimeric G proteins.
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6 July 2018
The Dbl family of oncogenes
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PubMed Central
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6 July 2018
Biological assays for Ras transformation
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PubMed Central
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6 July 2018
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
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6 July 2018
G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
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6 July 2018
A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells
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6 July 2018
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6 July 2018
Mechanisms for reversible regulation between G13 and Rho exchange factors
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28 October 2018
Rho family proteins and Ras transformation: the RHOad less traveled gets congested.
1 reference
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28 October 2018
Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways
1 reference
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28 October 2018
Cell cycle-dependent activation of Ras.
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28 October 2018
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12024019
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.22.12.4053-4061.2002
1 reference
stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PMC publication ID
133844
1 reference
stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
12024019
1 reference
stated in
Europe PubMed Central
PMC publication ID
133844
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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