(Q28190494)

English

Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA

scientific article (publication date: 20 July 2001)

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scholarly article

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Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA (English)

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1 reference

based on heuristic

inferred from title

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object named as

J Sondek

7

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Krister Wennerberg

object named as

K Wennerberg

4

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author name string

G W Reuther

1

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Q T Lambert

2

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M A Booden

3

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B Becknell

5

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G Marcucci

6

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M A Caligiuri

8

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C J Der

9

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language of work or name

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publication date

20 July 2001

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Journal of Biological Chemistry

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276

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27145-51

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29

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Lck regulates Vav activation of members of the Rho family of GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Identification of a novel guanine nucleotide exchange factor for the Rho GTPase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Oncogene ect2 is related to regulators of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Whither goest the RGS proteins?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

PDZ domains bind carboxy-terminal sequences of target proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Ras-mediated transcription activation: analysis by transient cotransfection assays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Biological assays for Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Analyses of transforming activity of Rho family activators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Purification of recombinant Rho/Rac/G25K from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Vav2 is an activator of Cdc42, Rac1, and RhoA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Cell cycle-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

A novel regulator of p21-activated kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

PDZ domains: targeting signalling molecules to sub-membranous sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Ras-Cdc25 and Rho-Dbl binding assays: complex formation in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Pak to the future

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The p21Rac/Cdc42-activated kinases (PAKs).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

A role for Rho in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The role of Rho in G protein-coupled receptor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

PEST sequences and regulation by proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Determination of GTP loading on Rho

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103565200

21 January 2018

Identifiers

10.1074/JBC.M103565200

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