(Q34281322)

25201980

1 August 2017

title

Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors (English)

1 reference

1 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Chihiro Hisatsune

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Akiko Terauchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kyoko Nakamura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Takayasu Higo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nobuyuki Nukina

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nagisa Matsumoto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Takeshi Nakamura

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Katsuhiko Mikoshiba

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

8 September 2014

1 reference

25201980

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

E3966-75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.

1 June 2020

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Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

6 July 2018

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6 July 2018

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6 July 2018

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Monitoring of transglutaminase 2 under different oxidative stress conditions.

6 July 2018

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Functional characterization of the P1059L mutation in the inositol 1,4,5-trisphosphate receptor type 1 identified in a Japanese SCA15 family.

6 July 2018

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Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

6 July 2018

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Mechanism of ER stress-induced brain damage by IP(3) receptor

6 July 2018

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Neurocognitive signs in prodromal Huntington disease

6 July 2018

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Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating

6 July 2018

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Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

6 July 2018

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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

6 July 2018

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Calcium-dependent conformational changes in inositol trisphosphate receptors.

6 July 2018

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A profiling platform for the characterization of transglutaminase 2 (TG2) inhibitors

6 July 2018

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Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly

6 July 2018

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G-protein-coupled receptor kinase-interacting proteins inhibit apoptosis by inositol 1,4,5-triphosphate receptor-mediated Ca2+ signal regulation

6 July 2018

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Synthetic partial agonists reveal key steps in IP3 receptor activation

6 July 2018

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Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders.

6 July 2018

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Burst-timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons

6 July 2018

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Transglutaminases and neurodegeneration

6 July 2018

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The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

6 July 2018

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Calcium signaling and neurodegenerative diseases

6 July 2018

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Surface accessibility and conformational changes in the N-terminal domain of type I inositol trisphosphate receptors: studies using cysteine substitution mutagenesis

6 July 2018

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The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions

6 July 2018

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Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.

6 July 2018

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Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.

6 July 2018

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Tissue transglutaminase: a novel pharmacological target in preventing toxic protein aggregation in neurodegenerative diseases

6 July 2018

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GTP-binding-defective forms of tissue transglutaminase trigger cell death

6 July 2018

1 reference

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Selective changes of resting-state networks in individuals at risk for Alzheimer's disease

6 July 2018

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6 July 2018

1 reference

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Dopaminergic signaling and striatal neurodegeneration in Huntington's disease

6 July 2018

1 reference

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

6 July 2018

1 reference

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Inositol trisphosphate receptor Ca2+ release channels.

6 July 2018

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Tissue transglutaminase inhibits autophagy in pancreatic cancer cells

6 July 2018

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Regulation of autophagy by the inositol trisphosphate receptor

6 July 2018

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Transglutaminase 2 in neurodegenerative disorders

6 July 2018

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IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

6 July 2018

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The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

6 July 2018

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Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

6 July 2018

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Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms

6 July 2018

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Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia

6 July 2018

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Elevated concentration of cerebrospinal fluid tissue transglutaminase in Parkinson's disease indicating apoptosis

6 July 2018

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Pathways towards and away from Alzheimer's disease

6 July 2018

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Inositol 1,4,5-trisphosphate receptors as signal integrators

6 July 2018

1 reference

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Inositol 1,4,5-trisphosphate receptor contains multiple cavities and L-shaped ligand-binding domains.

6 July 2018

1 reference

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Three-dimensional Rearrangements within Inositol 1,4,5-Trisphosphate Receptor by Calcium

6 July 2018

1 reference

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The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

6 July 2018

1 reference

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Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process

6 July 2018

1 reference

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Functional characterization of the type 1 inositol 1,4,5-trisphosphate receptor coupling domain SII(+/-) splice variants and the Opisthotonos mutant form

6 July 2018

1 reference

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The versatility and universality of calcium signalling

6 July 2018

1 reference

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Tissue transglutaminase does not contribute to the formation of mutant huntingtin aggregates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Ca(2+)-sensor region of IP(3) receptor controls intracellular Ca(2+) signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Calcium stores regulate the polarity and input specificity of synaptic modification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Intron-exon swapping of transglutaminase mRNA and neuronal Tau aggregation in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Intracellular targeting and homotetramer formation of a truncated inositol 1,4,5-trisphosphate receptor-green fluorescent protein chimera in Xenopus laevis oocytes: evidence for the involvement of the transmembrane spanning domain in endoplasmic ret

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Transglutaminase activity is increased in Alzheimer's disease brain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

The ligand binding site and transduction mechanism in the inositol-1,4,5-triphosphate receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Involvement of the C-terminus of the inositol 1,4,5-trisphosphate receptor in Ca2+ release analysed using region-specific monoclonal antibodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

50 years of allosteric interactions: the twists and turns of the models

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of purkinje cells in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Two Italian families with ITPR1 gene deletion presenting a broader phenotype of SCA15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Cerebrospinal fluid tissue transglutaminase as a biochemical marker for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Transglutaminase 2 is involved in autophagosome maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Substrate preference of transglutaminase 2 revealed by logistic regression analysis and intrinsic disorder examination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: looking for biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Arachidonic acid activates tissue transglutaminase and stress fiber formation via intracellular reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Behavioral and in vivo electrophysiological evidence for presymptomatic alteration of prefrontostriatal processing in the transgenic rat model for huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Two-state conformational changes in inositol 1,4,5-trisphosphate receptor regulated by calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Revisiting channel allostery: a coherent mechanism in IP₃ and ryanodine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Distinct roles of M1 and M3 muscarinic acetylcholine receptors controlling oscillatory and non-oscillatory [Ca2+]i increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409730111

Therapeutic effects of cystamine in a murine model of Huntington's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183345

Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of the S4-S5 linker and C-terminal tail in inositol 1,4,5-trisphosphate receptor function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25201980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1409730111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25201980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25201980%20AND%20SRC:MED&resulttype=core&format=json