(Q46140335)

19 December 2017

title

50 years of allosteric interactions: the twists and turns of the models (English)

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19 December 2017

1

Jean-Pierre Changeux

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19 December 2017

publication date

23 October 2013

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19 December 2017

Nature Reviews Molecular Cell Biology

published in

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19 December 2017

volume

14

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19 December 2017

issue

12

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19 December 2017

page(s)

819-829

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19 December 2017

https://scigraph.springernature.com/pub.10.1038/nrm3695

exact match

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cites work

The feedback control mechanisms of biosynthetic L-threonine deaminase by L-isoleucine

1 reference

Teleonomic mechanisms in cellular metabolism, growth, and differentiation

21 January 2018

1 reference

Allosteric proteins and cellular control systems

21 January 2018

1 reference

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

21 January 2018

1 reference

The origins of allostery: from personal memories to material for the future

21 January 2018

1 reference

STRUCTURAL ALTERATIONS IN CRYSTALLINE GLUTAMIC DEHYDROGENASE INDUCED BY STEROID HORMONES.

21 January 2018

1 reference

Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis

21 January 2018

1 reference

Allosteric Interactions on Biosynthetic L-threonine Deaminase from E. coli K12

21 January 2018

1 reference

The role of dynamic conformational ensembles in biomolecular recognition

21 January 2018

1 reference

Allostery and cooperativity revisited

21 January 2018

1 reference

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

21 January 2018

1 reference

On the cooperativity of biological membranes

21 January 2018

1 reference

Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

21 January 2018

1 reference

The binding of nicotinamide-adenine dinucleotide to yeast d-glyceraldehyde-3-phosphate dehydrogenase: temperature-jump relaxation studies on the mechanism of an allosteric enzyme

21 January 2018

1 reference

Allosteric Interactions in Aspartate Transcarbamylase. II. Evidence for Different Conformational States of the Protein in the Presence and Absence of Specific Ligands

21 January 2018

1 reference

Allosteric interactions in aspartate transcarbamylase. 3. Interpretation of experimental data in terms of the model of Monod, Wyman, and Changeux

21 January 2018

1 reference

Trendspotting in the Protein Data Bank

21 January 2018

1 reference

The RCSB Protein Data Bank: new resources for research and education

21 January 2018

1 reference

Allostery and the Monod-Wyman-Changeux model after 50 years

21 January 2018

1 reference

Structural, evolutionary, and assembly principles of protein oligomerization

21 January 2018

1 reference

A model for reading morphogenetic gradients: autocatalysis and competition at the gene level

21 January 2018

1 reference

A hierarchical coherent-gene-group model for brain development.

21 January 2018

1 reference

Extensions of the Allosteric Model for Haemoglobin

21 January 2018

1 reference

The stereochemical mechanism of the cooperative effects in hemoglobin revisited

21 January 2018

1 reference

The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin.

21 January 2018

1 reference

Unsuspected pathway of the allosteric transition in hemoglobin

21 January 2018

1 reference

Coarse-grained and all-atom modeling of structural states and transitions in hemoglobin

21 January 2018

1 reference

Structure and mechanisms of Escherichia coli aspartate transcarbamoylase

21 January 2018

1 reference

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

21 January 2018

1 reference

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

21 January 2018

1 reference

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

21 January 2018

1 reference

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

21 January 2018

1 reference

Structure and pharmacology of pentameric receptor channels: from bacteria to brain

21 January 2018

1 reference

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

21 January 2018

1 reference

The energy and work of a ligand-gated ion channel

21 January 2018

1 reference

A locally closed conformation of a bacterial pentameric proton-gated ion channel

21 January 2018

1 reference

Conformational selection in trypsin-like proteases.

21 January 2018

1 reference

Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.

21 January 2018

1 reference

Unraveling the structural basis of GPCR activation and inactivation.

21 January 2018

1 reference

Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

21 January 2018

1 reference

Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors

21 January 2018

1 reference

Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer

21 January 2018

1 reference

Restructuring G-protein- coupled receptor activation

21 January 2018

1 reference

Allosteric communication occurs via networks of tertiary and quaternary motions in proteins

21 January 2018

1 reference

On the role of frustration in the energy landscapes of allosteric proteins

21 January 2018

1 reference

Modulation of allostery by protein intrinsic disorder

21 January 2018

1 reference

Allostery and the lac Operon

21 January 2018

1 reference

Architecture and membrane interactions of the EGF receptor

21 January 2018

1 reference

Conformational coupling across the plasma membrane in activation of the EGF receptor

21 January 2018

1 reference

Order-disorder transitions govern kinetic cooperativity and allostery of monomeric human glucokinase

21 January 2018

1 reference

Structure and Allostery of the PKA RII Tetrameric Holoenzyme

21 January 2018

1 reference

Protein activity regulation by conformational entropy

21 January 2018

1 reference

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein.

21 January 2018

1 reference

Allostery without conformation change: modelling protein dynamics at multiple scales

21 January 2018

1 reference

Structure and allostery of the chaperonin GroEL.

21 January 2018

1 reference

Allosteric mechanisms can be distinguished using structural mass spectrometry

21 January 2018

1 reference

The discovery and structural investigation of the IP₃ receptor and the associated IRBIT protein

21 January 2018

1 reference

Allosteric effects in the regulation of 26S proteasome activities

21 January 2018

1 reference

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

21 January 2018

1 reference

Structural insights into anaphase-promoting complex function and mechanism

21 January 2018

1 reference

Virus maturation targets the protein capsid to concerted disassembly and unfolding

21 January 2018

1 reference

The N-terminal extension of cardiac troponin T stabilizes the blocked state of cardiac thin filament

21 January 2018

1 reference

Virus assembly and maturation: auto-regulation through allosteric molecular switches

21 January 2018

1 reference

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

21 January 2018

1 reference

Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors

21 January 2018

1 reference

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

21 January 2018

1 reference

The concept of allosteric modulation: an overview

21 January 2018

1 reference

Identification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513.

21 January 2018

1 reference

Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors

21 January 2018

1 reference

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

21 January 2018

1 reference

Principles of activation and permeation in an anion-selective Cys-loop receptor

21 January 2018

1 reference

A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulation

21 January 2018

1 reference

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

21 January 2018

1 reference

The Energy Landscapes and Motions of Proteins

21 January 2018

1 reference

Allostery in disease and in drug discovery

21 January 2018

1 reference

Allostery and population shift in drug discovery

21 January 2018

1 reference

21 January 2018

A footnote on allostery.

1 reference

Cooperativity of allosteric receptors

21 January 2018

1 reference

Trade-offs and constraints in allosteric sensing

21 January 2018

1 reference

Statistical mechanics of Monod-Wyman-Changeux (MWC) models

21 January 2018

1 reference

Conformational selection or induced fit? 50 years of debate resolved

21 January 2018

1 reference

T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control

21 January 2018

1 reference

Allostery and cooperativity in Escherichia coli aspartate transcarbamoylase

21 January 2018

1 reference

Escherichia coli aspartate transcarbamylase: the relation between structure and function

21 January 2018

1 reference

Crystal structure of the lactose operon repressor and its complexes with DNA and inducer

21 January 2018

1 reference

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

In vitro phosphorylation of the acetylcholine receptor

21 January 2018

1 reference

Evidence for a negative-feedback mechanism in the biosynthesis of isoleucine

21 January 2018

1 reference

[Effect of L-threonine and L-isoleucine analogs on L-threonine desaminase]

31 March 2020

1 reference

From feedback inhibition to allostery: the enduring example of aspartate transcarbamoylase

31 March 2020

1 reference

Coenzyme binding, observed by fluorescence enhancement, apparently unrelated to the enzymic activity of glutamic dehydrogenase

31 March 2020

1 reference

Inhibition of glutamic dehydrogenase by o-phenanthroline and its analogs

31 March 2020

1 reference

Activation of acetyl-CoA carboxylase and associated alteration of sedimentation characteristics of the enzyme

31 March 2020

1 reference

Enzyme flexibility and enzyme action

31 March 2020

1 reference

Allosteric interactions in aspartate transcarbamylase. I. Binding of specific ligands to the native enzyme and its isolated subunits

31 March 2020

1 reference

Kinetics of the allosteric interactions of phosphofructokinase from Escherichia coli

31 March 2020

1 reference

Unveiling the timescale of the R-T transition in human hemoglobin

31 March 2020

1 reference

A gating mechanism of pentameric ligand-gated ion channels

31 March 2020

1 reference

Protein function and allostery: a dynamic relationship

31 March 2020

1 reference

The propagation of allosteric states in large multiprotein complexes

31 March 2020

1 reference

X-ray analysis of hemoglobin

31 March 2020

1 reference

Glutamic dehydrogenase. I. The effect of coenzyme on the sedimentation velocity and kinetic behavior

31 March 2020

1 reference

12 December 2020

Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism

1 reference

12 December 2020

The enzymology of control by feedback inhibition.

1 reference

12 December 2020

ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHESIZED L-THREONINE DEAMINASE. VI. GENERAL DISCUSSION

1 reference

12 December 2020

Mapping the domain of troponin T responsible for the activation of actomyosin ATPase activity. Identification of residues involved in binding to actin

1 reference

12 December 2020

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis

1 reference

12 December 2020

Molecular properties and transformations of glycogen phosphorylase in animal tissues

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM3695

1 reference

19 December 2017

1 reference

19 December 2017