(Q41775482)

9 October 2017

Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. (English)

1 reference

9 October 2017

1 reference

3

1 reference

9 October 2017

Raymond C Stevens

4

0 references

Reto Horst

series ordinal

2

object named as

Reto Horst

1 reference

9 October 2017

5

Kurt Wüthrich

1 reference

9 October 2017

Jeffrey J Liu

1

1 reference

PMC publication ID

3292700

9 October 2017

language of work or name

English

0 references

publication date

19 January 2012

1 reference

9 October 2017

1 reference

9 October 2017

335

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9 October 2017

6072

1 reference

9 October 2017

1106-1110

1 reference

Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex

9 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Multiple ligand-specific conformations of the β2-adrenergic receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Crystal structure of the β2 adrenergic receptor-Gs protein complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structural insights into agonist-induced activation of G-protein-coupled receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

β-Arrestin-mediated receptor trafficking and signal transduction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structure of an agonist-bound human A2A adenosine receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structure and function of an irreversible agonist-β(2) adrenoceptor complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Ligand binding and micro-switches in 7TM receptor structures

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Crystal structure of opsin in its G-protein-interacting conformation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

beta-arrestin-biased agonism at the beta2-adrenergic receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: insights from fluorescence resonance energy transfer studies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

19F NMR studies of solvent exposure and peptide binding to an SH3 domain

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

When 7 transmembrane receptors are not G protein-coupled receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Membrane protein-lipid interactions in mixed micelles studied by NMR spectroscopy with the use of paramagnetic reagents

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Use of 19F NMR to probe protein structure and conformational changes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

19F nuclear magnetic resonance studies of aqueous and transmembrane receptors. Examples from the Escherichia coli chemosensory pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

The selectivity of beta-adrenoceptor agonists at human beta1-, beta2- and beta3-adrenoceptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292700

Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22267580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22267580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1215802

LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1215802

Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1215802

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1215802

The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1215802

Identifiers

DOI

10.1126/SCIENCE.1215802

1 reference

9 October 2017

1 reference

PMC publication ID

3292700

9 October 2017

PubMed publication ID

22267580

1 reference

PMC publication ID

3292700