(Q40020328)

English

Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure

scientific article published on 23 December 2007

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure (English)

1 reference

Europe PubMed Central

16 September 2017

G protein-coupled receptor

0 references

Raymond C. Stevens

object named as

Raymond C Stevens

3

0 references

author name string

Christopher B Roth

1

1 reference

Europe PubMed Central

16 September 2017

Michael A Hanson

2

1 reference

Europe PubMed Central

16 September 2017

language of work or name

0 references

publication date

23 December 2007

1 reference

Europe PubMed Central

16 September 2017

Journal of Molecular Biology

1 reference

Europe PubMed Central

16 September 2017

376

1 reference

Europe PubMed Central

16 September 2017

5

1 reference

Europe PubMed Central

16 September 2017

1305-1319

1 reference

Europe PubMed Central

16 September 2017

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

Crystal Structure of a Thermally Stable Rhodopsin Mutant

1 reference

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22 September 2017

Role of group-conserved residues in the helical core of beta2-adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization

1 reference

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22 September 2017

Molecular mechanism of 7TM receptor activation--a global toggle switch model

1 reference

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22 September 2017

Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors.

1 reference

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22 September 2017

Recognition of transmembrane helices by the endoplasmic reticulum translocon.

1 reference

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Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors

1 reference

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22 September 2017

Coupling of retinal isomerization to the activation of rhodopsin

1 reference

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22 September 2017

Helix packing moments reveal diversity and conservation in membrane protein structure.

1 reference

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A colourless green fluorescent protein homologue from the non-fluorescent hydromedusa Aequorea coerulescens and its fluorescent mutants

1 reference

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22 September 2017

Stabilizing membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

Hydrogen bonds with pi-acceptors in proteins: frequencies and role in stabilizing local 3D structures

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

22 September 2017

Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

25 September 2017

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

25 September 2017

Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

17 June 2018

Building a thermostable membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

17 June 2018

Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

17 June 2018

Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

20 August 2018

Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

20 August 2018

Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines

1 reference

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20 August 2018

Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

20 August 2018

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

20 August 2018

The occurrence of C--H...O hydrogen bonds in alpha-helices and helix termini in globular proteins

1 reference

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20 August 2018

Rescuing the traffic-deficient mutants of rat mu-opioid receptors with hydrophobic ligands

1 reference

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20 August 2018

An opsin mutant with increased thermal stability

1 reference

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20 August 2018

Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292833

20 August 2018

Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2.

1 reference

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20 August 2018

Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.

1 reference

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20 August 2018

C-H...pi-interactions in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18222471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18222471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18222471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C--H...O hydrogen bond involving proline residues in alpha-helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18222471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GRIS: glycoprotein-hormone receptor information system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18222471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2007.12.028

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

ResearchGate publication ID

0 references

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