(Q26852212)

1

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Jean-Pierre Changeux

6

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author name string

Frédéric Poitevin

2

1 reference

Marie S. Prevost

3

1 reference

Ludovic Sauguet

4

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language of work or name

1 reference

6 June 2012

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1 reference

20

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PubMed

issue

6

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PubMed

page(s)

941-56

1 reference

Enzyme flexibility and enzyme action

PubMed

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

50th anniversary of the word "allosteric".

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The Evolution of Pentameric Ligand-Gated Ion Channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Protein normal-mode dynamics: trypsin inhibitor, crambin, ribonuclease and lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ligand-gated ion channels in the brain: the amino acid receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

NMR structure of the transmembrane domain of the n-acetylcholine receptor β2 subunit

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Allosteric modulation of nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Insight in nAChR subtype selectivity from AChBP crystal structures.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Allosteric modulators of the α4β2 subtype of neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Linking the Acetylcholine Receptor-Channel Agonist-Binding Sites with the Gate

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ion selectivity mechanism in a bacterial pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Temperature dependence of acetylcholine receptor channels activated by different agonists

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Global twisting motion of single molecular KcsA potassium channel upon gating

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-α-subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Conserved site for neurosteroid modulation of GABA A receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Molecular targets and mechanisms for ethanol action in glycine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Brain nicotinic acetylcholine receptors: native subtypes and their relevance.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Binding, activation and modulation of Cys-loop receptors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Threonine in the selectivity filter of the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The location of the gate in the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

From muscle endplate to brain synapses: a short history of synapses and agonist-activated ion channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the beta and delta chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Conformational changes in the nicotinic acetylcholine receptor during gating and desensitization

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Tryptophan side chain electrostatic interactions determine edge-to-face vs parallel-displaced tryptophan side chain geometries in the designed beta-hairpin "trpzip2".

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Input–Output Relation of a Single Synapse

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Biological Sciences: Isolation of the Cholinergic Receptor Protein of Torpedo Electric Tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Quaternary structure of the acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Acetylcholine receptor channel imaged in the open state

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structure and gating mechanism of the acetylcholine receptor pore

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Principal pathway coupling agonist binding to channel gating in nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Probing ion-channel pores one proton at a time

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

On the nature of partial agonism in the nicotinic receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Nicotine binding to brain receptors requires a strong cation-pi interaction

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Detection and trapping of intermediate states priming nicotinic receptor channel opening

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structural basis for the coupling between activation and inactivation gates in K(+) channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structural mechanism of C-type inactivation in K(+) channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Principles of activation and permeation in an anion-selective Cys-loop receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Emerging structure of the nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A locally closed conformation of a bacterial pentameric proton-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

AQUASOL: An efficient solver for the dipolar Poisson-Boltzmann-Langevin equation

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A speed limit for conformational change of an allosteric membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Pore conformations and gating mechanism of a Cys-loop receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Molecular tuning of fast gating in pentameric ligand-gated ion channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Unliganded gating of acetylcholine receptor channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Nicotinic pharmacophore: the pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Design and control of acetylcholine receptor conformational change

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structural basis for alcohol modulation of a pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Affinity labeling of the acetylcholine-receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Use of a snake venom toxin to characterize the cholinergic receptor protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Dynamics of a small globular protein in terms of low-frequency vibrational modes

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Harmonic dynamics of proteins: normal modes and fluctuations in bovine pancreatic trypsin inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Spontaneous openings of the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The multiple phenotypes of allosteric receptor mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Up-regulation of cell-surface alpha4beta2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Subunit symmetry at the extracellular domain-transmembrane domain interface in acetylcholine receptor channel gating

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

In glycine and GABA(A) channels, different subunits contribute asymmetrically to channel conductance via residues in the extracellular domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Creating an 7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein: CRYSTALLOGRAPHIC AND LIGAND SELECTIVITY ANALYSES

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Modulation of nicotinic acetylcholine receptor conformational state by free fatty acids and steroids

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Characterization of the effects of charged residues in the intracellular loop on ion permeation in alpha1 glycine receptor channels.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A lipid-dependent uncoupled conformation of the acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Three-dimensional structure of the nicotinic acetylcholine receptor and location of the major associated 43-kD cytoskeletal protein, determined at 22 A by low dose electron microscopy and x-ray diffraction to 12.5 A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The location of a closed channel gate in the GABAA receptor channel.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Acetylcholine receptor gating: movement in the alpha-subunit extracellular domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Energetics of gating at the apo-acetylcholine receptor transmitter binding site

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The long activations of α2 glycine channels can be described by a mechanism with reaction intermediates ("flip").

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Activation and blockade of beta adrenoceptors in common cardiac disorders

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Interaction at End-Plate Receptors between Different Choline Derivatives

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Packing of aromatic rings against tryptophan residues in proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A study of the desensitization produced by acetylcholine at the motor end-plate

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Thinking in cycles: MWC is a good model for acetylcholine receptor-channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Determinants of zinc potentiation on the alpha4 subunit of neuronal nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Allosteric mechanisms of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Isosterism and competitive phenomena in drugs; a study of structure-activity relationships in agents acting upon autonomic effector cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ethanol's molecular targets

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Allostery and the Monod-Wyman-Changeux model after 50 years

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

GABAA receptor channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Allosteric receptors: from electric organ to cognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Nicotinic receptors at the amino acid level

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Molecular structure and function of the glycine receptor chloride channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Decrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network model

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Mutation of glutamate 155 of the GABAA receptor beta2 subunit produces a spontaneously open channel: a trigger for channel activation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Functional complementation of Glra1(spd-ot), a glycine receptor subunit mutant, by independently expressed C-terminal domains.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

A portable site: a binding element for 17β-estradiol can be placed on any subunit of a nicotinic α4β2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Functional relationships between agonist binding sites and coupling regions of homomeric Cys-loop receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Incorporating dipolar solvents with variable density in Poisson-Boltzmann electrostatics

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Quorum sensing and bacterial social interactions in biofilms

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021

Conformational selection or induced fit? 50 years of debate resolved

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2012.05.003

7 January 2021