(Q35580546)

9 August 2017

title

Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation (English)

1 reference

9 August 2017

Single-Channel and Structural Foundations of Neuronal α7 Acetylcholine Receptor Potentiation (English)

1 reference

10.1523/JNEUROSCI.2652-11.2011

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.2652-11.2011

13 December 2024

author name string

Jeremías Corradi

3

1 reference

9 August 2017

Cecilia Bouzat

4

1 reference

9 August 2017

Corrie J. B. daCosta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

13 December 2024

Chris R. Free

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

13 December 2024

Steven M. Sine

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

13 December 2024

language of work or name

English

0 references

publication date

1 September 2011

1 reference

9 August 2017

28 September 2011

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21957249

full work available at URL

13 December 2024

https://www.jneurosci.org/content/jneuro/31/39/13870.full.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

https://europepmc.org/articles/PMC3226716

13 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

https://europepmc.org/articles/PMC3226716?pdf=render

13 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

https://doi.org/10.1523/jneurosci.2652-11.2011

13 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21957249

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.2652-11.2011

13 December 2024

1 reference

10.1523/JNEUROSCI.2652-11.2011

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.2652-11.2011

13 December 2024

published in

Journal of Neuroscience

1 reference

9 August 2017

volume

31

1 reference

9 August 2017

issue

39

1 reference

9 August 2017

page(s)

13870-13879

1 reference

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Principles of activation and permeation in an anion-selective Cys-loop receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

12 July 2018

1 reference

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Positive and negative modulation of nicotinic receptors

12 July 2018

1 reference

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Neuronal nicotinic acetylcholine receptors - targets for the development of drugs to treat cognitive impairment associated with schizophrenia and Alzheimer's disease

12 July 2018

1 reference

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Physiological concentrations of choline activate native alpha7-containing nicotinic acetylcholine receptors in the presence of PNU-120596 [1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)-urea].

12 July 2018

1 reference

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Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia

12 July 2018

1 reference

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Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

12 July 2018

1 reference

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Single-channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors

12 July 2018

1 reference

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Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.

12 July 2018

1 reference

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Allosteric modulators of the alpha7 nicotinic acetylcholine receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Allosteric modulation of nicotinic acetylcholine receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the path

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators

12 July 2018

1 reference

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Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

12 July 2018

1 reference

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Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

12 July 2018

1 reference

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Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors

12 July 2018

1 reference

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Single-channel kinetic analysis of chimeric alpha7-5HT3A receptors.

12 July 2018

1 reference

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Allosteric modulation of ligand-gated ion channels

12 July 2018

1 reference

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A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.

12 July 2018

1 reference

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Ric-3 promotes functional expression of the nicotinic acetylcholine receptor alpha7 subunit in mammalian cells

12 July 2018

1 reference

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The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid

12 July 2018

1 reference

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

12 July 2018

1 reference

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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

12 July 2018

1 reference

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Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Production of high-titer helper-free retroviruses by transient transfection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Data transformations for improved display and fitting of single-channel dwell time histograms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Opening rate of acetylcholine receptor channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

[3H]Benzophenone photolabeling identifies state-dependent changes in nicotinic acetylcholine receptor structure

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

The correction of alpha7 nicotinic acetylcholine receptor concentration-response relationships in Xenopus oocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226716

Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21957249

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.2652-11.2011

1 reference

release_yquryvbjordh5fnodlmudwe6e4

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yquryvbjordh5fnodlmudwe6e4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3226716

1 reference

9 August 2017

1 reference